2024
DOI: 10.3389/fnins.2024.1375892
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Associations of cerebrospinal fluid profiles with severity and mortality risk of amyotrophic lateral sclerosis

Jiajia Fu,
Xiaohui Lai,
Qianqian Wei
et al.

Abstract: BackgroundThe relationship between routine cerebrospinal fluid (CSF) testing and the disease phenotype of amyotrophic lateral sclerosis (ALS) is unclear, and there are some contradictions in current studies.MethodsThis study aimed to analyze the relationship between CSF profiles and disease phenotype in ALS patients. We collected 870 ALS patients and 96 control subjects admitted to West China Hospital of Sichuan University. CSF microprotein, albumin, IgG, index of IgG (IgGindex), albumin quotient (QALB), and s… Show more

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