“…These results reflect findings from previous studies that have also found significant changes within the PUFA profiles of individuals with cognitive impairment [ 70 , 71 , 72 , 73 ]. It has been shown previously within a number of epidemiological studies that maintaining sufficient levels of PUFAs and, in particular, DHA and precursors of n-3 synthesis, such as α-linolenic acid, may be protective against age-related cognitive decline or dementia, including AD [ 32 , 52 , 70 , 74 , 75 , 76 , 77 , 78 , 79 , 80 ]. The potential protective effects of PUFAs in relation to cognitive impairment may be related to lowering the risk for heart diseases [ 70 , 81 ] or non-haemorrhagic stroke [ 82 ], which has been shown to escalate the risk of developing dementia and its major subtypes [ 83 , 84 ].…”