Associations of obesity and serum leptin level with elevated blood pressure among urban secondary school students of a northeastern city of India: A baseline observation

Goswami, Bidhan; Bhattacharjya, Himadri; Sengupta, Shauli; Bhattacharjee, Bhaskar

doi:10.4103/jfmpc.jfmpc_1118_19

Cited by 5 publications

(2 citation statements)

References 34 publications

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“…while, Many obese people for unexplained reasons, acquire resistance to leptin's weight-loss and satiety benefits, just as patients with type 2 diabetes (DM-type 2) develop resistance to but retain the effects of the hormone insulin. the leptin-mediated sympathetic system activates cells in non-thermogenic tissues like the heart, kidneys, and adrenals, and hence plays a major part in the physiological processes of vascular tendons, renal hemodynamics, and hypertension (12).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of serum leptin levels in hypertensive men in Thi Qar City-Iraq (a comparative study)

2023

JPTCP

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Leptin, a hormone secreted from adipose tissue, is closely related to inflammatory, metabolic, and homeostasis factors. This hormone has also been shown to perform a significant involvement in the development of hypertension. This study aimed to measure serum leptin levels and lipid profiles in hypertensive males and compare them with control healthy males that were congruent with age and BMI. The current study included 50 subjects from Thi Qar city people, and it was divided into two groups. The first group included 25 hypertensive adult male patients who had BMI (Mean±SD 27.98±2.9), while the second group included 25 healthy adults males as a control group who had BMI (Mean±SD 27.41±3.5). The current study included evaluating serum leptin and lipid profile of studied groups after 8-12 hours of fasting state. It was found that the level of leptin was high significant variance in hypertensive adults males compared to the healthy control group (22.4±3.4ng/ml against 13.9±1.6 ng/ml, respectively; p<0.03), A good correlation was also found between leptin levels and systolic, diastolic blood pressure, and body fat percentage ( r=0. 648, r=0.506, and r=0.490, respectively). It was also found that moreover male patients had a bad Lipid profile when compared to the healthy control group.

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Section: Introductionmentioning

confidence: 99%

Evaluation of serum leptin levels in hypertensive men in Thi Qar City-Iraq (a comparative study)

2023

JPTCP

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“…The prevalence of prehypertension (PHT) and hypertension (HTN) among urban school-going adolescents in a northeastern city of India was found to be 42.40% and 15.70%, respectively. [ 1 ] Epidemiological studies have shown associations between low Vitamin D 3 levels, dyslipidemia, and cardiovascular diseases. [ 2 ] Studies across different parts of Asia show a widespread prevalence of Vitamin D insufficiency within both sexes and all age groups.…”

Section: Introductionmentioning

confidence: 99%

Hypovitaminosis D, dyslipidemia, and thyroid dysfunction among adolescents and their associations with blood pressure in a Northeastern City of India

Goswami

Bhattacharjya

Sengupta

et al. 2021

Indian J Community Med

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Blood Pressure Correlates with Serum Leptin and Body Mass Index in Overweight Male Saudi Students

Alaamri

Serafi

Hussain

et al. 2023

JPM

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The precise association of serum leptin (Lep) with the body mass index (BMI) and blood pressure (BP) is not well known for understanding their involvement in health and disease. Hence, the present study was conducted to investigate the association of BP, BMI and serum Lep levels in young normal-weight (NW) and overweight (OW) male Saudi students. The NW (n: 198) and OW (n: 192) male subjects in the age range of 18–20 years were consulted. The BP was measured with a mercury sphygmomanometer. Leptin Human ELISA Kits were employed for the determination of the serum Lep levels. The mean ± SD values of BMI (kg/m2), Lep (ng/mL), systolic BP (SBP; mmHg), and diastolic BP (DBP; mmHg) all showed significant differences for young OW vs. NW subjects as: 27.52 ± 1.42 vs. 21.49 ± 2.03; 10.70 ± 4.67 vs. 4.68 ± 1.91; 121.37 ± 2.59 vs. 118.51 ± 1.54 and 81.44 ± 1.97 vs. 78.79 ± 1.44, respectively. All associations (among BMI, Lep, SBP and DBP) showed a positive linear and significant correlation, except the nonsignificant correlation of BMI and SBP for the NW group. Other variables showing significant variation for NW vs. OW subjects were: interleukin-6, high sensitivity C-reactive protein, apelin (APLN) and resistin. Serum APLN correlated significantly with Lep, BMI, SBP and DBP in lower and higher levels of BMI, with considerable progressive patterns in both the NW and OW groups and subgroups. The present study in young Saudi male students presents significant variations for BP and serum leptin levels, and a significant positive linear association among serum leptin, BMI and BP.

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Associations of obesity and serum leptin level with elevated blood pressure among urban secondary school students of a northeastern city of India: A baseline observation

Cited by 5 publications

References 34 publications

Evaluation of serum leptin levels in hypertensive men in Thi Qar City-Iraq (a comparative study)

Evaluation of serum leptin levels in hypertensive men in Thi Qar City-Iraq (a comparative study)

Hypovitaminosis D, dyslipidemia, and thyroid dysfunction among adolescents and their associations with blood pressure in a Northeastern City of India

Blood Pressure Correlates with Serum Leptin and Body Mass Index in Overweight Male Saudi Students

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