Associations of pre-lambing body condition score and serum β-hydroxybutyric acid and non-esterified fatty acids concentrations with periparturient health of Chios dairy ewes

Karagiannis, I.; Panousis, Nikolaos; Kiossis, Evangelos; Tsakmakidis, Ιoannis; Lafi, Shawkat Q.; Arsenos, G.; Boscos, C.; Brozos, Christos

doi:10.1016/j.smallrumres.2014.05.001

Cited by 14 publications

(18 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Relevant information correlating BHBA concentrations after lambing with short and longer-term milk yields are lacking in the accessed literature for dairy ewes. High levels of BHBA and NEFA before lambing predispose to several periparturient health disorders, such as clinical mastitis (Karagiannis et al 2014). The results of the present study indicated that increased pre-lambing BHBA (-30d, -15d) and NEFA (-30d) concentrations were positively correlated with the count of the halves with increased SCC after lambing (15 and 30 DIM).…”

Section: Figure1supporting

confidence: 48%

“…BHBA concentration 30 days before parturition was weakly positively correlated with milk yield produced until 30 DIM. It was previously reported that, blood BHBA concentration increases during late gestation and may reach its peak before or around lambing (Raoofi et al 2013;Karagiannis et al 2014). It is possible that the ewes with potential for higher milk production could have higher energy metabolism before lambing, expressed as increased BHBA concentrations.…”

Section: Discussionmentioning

confidence: 98%

“…However, breeds or individuals with higher potential in milk production, may confront increased difficulty in controlling energy balance, especially during the period around parturition (Bizelis et al 2000). Although periparturient period in dairy ewes is not precisely defined, its importance for health and productivity has been noted (Charismiadou et al 2000, Theodorou et al 2007, Mavrogianniand Brozos 2008, Karagiannis et al 2014.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Associations of periparturient β-hydroxybutyric acid and non-esterified fatty acids blood serum concentrations with milk yield, milk composition and milk somatic cells count of intensively managed Chios dairy ewes

Karagiannis

Brozos

Kiossis

et al. 2019

J Hellenic Vet Med Soc

Self Cite

View full text Add to dashboard Cite

This Research Paper addresses the hypothesis whether in dairy ewes: periparturient β-hydroxybutyric acid (BHBA) and non-esterified fatty acids (NEFA) concentrations are associated with milk yield, composition and udder halves with increased somatic cell counts (SCC ≥ 0.5 × 106 cells/mL). A total of 186 Chios ewes reared under intensive system were used for this research. Serum BHBA and NEFA concentrations were measured before lambing (-30d, -15d), and BHBA concentrations after lambing (+7d, +15d, +30d, +45d). Milk samples were collected at 15, 30 and 45days in milk (DIM). Total milk yield (MY) of the first 30, 60 and 90 DIM and total fortnightly milk yield (FMY) produced from 15 to 59 DIM were recorded. Positive associations between BHBA at +7d and MY of the first 30, 60 and 90 DIM were revealed (P < 0.001). For every increased unit of BHBA at +15d, +30d and +45d, FMY was decreased (DIM: 15 – 29 and 30 – 44) (P = 0.001 and P = 0.015, respectively) or increased (DIM: 45 – 59) (P < 0.001). BHBA before lambing (-30d, -15d) affected the number of halves presented SCC ≥ 0.5 × 106 cells/mL at 15 and 30 DIM (P = 0.011, P = 0.014, P = 0.009, P = 0.096, respectively). Finally, for every increased unit of BHBA during lactation (+15d, +30d, +45d) a decrease in the concentration of milk in proteins, solids not fat and lactose was noted (P < 0.001). This work demonstrates the associations of periparturient blood biochemical parameters (BHBA, NEFA) with milk yield and specific milk production characteristics.

show abstract

Section: Figure1supporting

confidence: 48%

Section: Discussionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Associations of periparturient β-hydroxybutyric acid and non-esterified fatty acids blood serum concentrations with milk yield, milk composition and milk somatic cells count of intensively managed Chios dairy ewes

Karagiannis

Brozos

Kiossis

et al. 2019

J Hellenic Vet Med Soc

Self Cite

View full text Add to dashboard Cite

show abstract

“…Karagiannis et al . () indicate that the energy state of the periparturient ewes can be estimated measuring the BHOB, as the BHOB concentration indicates the integrity of the oxidation of fats in the liver.…”

Section: Introductionmentioning

confidence: 99%

“…BHOB serum concentration, considering dietary fluctuations, is considered a sensitive indicator of the impaired metabolism of glucose and lipids in ovine and bovine ketosis (Roubies et al, 2003). Karagiannis et al (2014) indicate that the energy state of the periparturient ewes can be estimated measuring the BHOB, as the BHOB concentration indicates the integrity of the oxidation of fats in the liver.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of a fibrate, specific stimulant of PPARα, as a therapeutic alternative to the treatment of clinical ovine pregnancy toxaemia

Silva¹,

Cal-Pereyra²,

Benech³

et al. 2016

Vet Pharm & Therapeutics

View full text Add to dashboard Cite

Ovine pregnancy toxaemia is a metabolic disorder affecting sheep in their last 6 weeks of pregnancy as a result of their inability to maintain adequate energy homoeostasis. Different alternative treatments are available with variable results. The aim of this research was to evaluate a peroxisome proliferator-activated receptor alpha (PPARα) stimulant as an alternative to treat clinical pregnancy toxaemia. Thirty-three adult sheep, with known gestation date and carrying a single foetus, were fasted from day 130 of gestation until animals showed clinical disease. From that moment onwards, sheep were treated during 6 days with three different therapeutic alternatives: 10 mg/kg of 2-methyl-2-phenoxy-propionic acid; 10 mg/kg of 2-methyl-2-phenoxy-propionic acid + 100 mL of propylene glycol oral; or 100 mL of propylene glycol oral. Glycaemia and serum β-hydroxybutyrate (BHOB) were determined daily. Liver biopsies were taken at day 130 of gestation, at the beginning and end of treatments and at 5 days postpartum, evaluating the extent and degree of the steatosis lesion. Even though in sheep treated with 2-methyl-2-phenoxy-propionic acid, serum concentrations of glucose and BHOB recovered more slowly, we conclude that 2-methyl-2-phenoxy-propionic acid alone or combined with propylene glycol can be used as an alternative to effectively treat fatty liver, and therefore pregnancy toxaemia.

show abstract

Advances in managing pregnancy toxaemia in sheep

Crilly¹,

Phythian²,

Evans³

2021

In Practice

View full text Add to dashboard Cite

Background: Ovine pregnancy toxaemia (OPT) is a metabolic disorder of ewes in late pregnancy. Cases are typically seen in ewes carrying multiple fetuses, hence the alternative name of ‘twin lamb disease’. The disease has been well known for many years. Despite this, the toll inflicted by the disease remains considerable, due both to the poor prognosis of clinically affected animals, even with appropriate treatment, and the impact of the provoking factors of under‐nutrition and concomitant disease on ewe morbidity, lamb survival and flock productivity. Cases of OPT are an indication of shortcomings in the management of late‐pregnancy ewes. Aim of the article: This article provides an update on the aetiopathogenesis, diagnosis, treatment and prevention of OPT, drawing on recently published studies.

show abstract

Associations of pre-lambing body condition score and serum β-hydroxybutyric acid and non-esterified fatty acids concentrations with periparturient health of Chios dairy ewes

Cited by 14 publications

References 27 publications

Associations of periparturient β-hydroxybutyric acid and non-esterified fatty acids blood serum concentrations with milk yield, milk composition and milk somatic cells count of intensively managed Chios dairy ewes

Associations of periparturient β-hydroxybutyric acid and non-esterified fatty acids blood serum concentrations with milk yield, milk composition and milk somatic cells count of intensively managed Chios dairy ewes

Evaluation of a fibrate, specific stimulant of PPARα, as a therapeutic alternative to the treatment of clinical ovine pregnancy toxaemia

Advances in managing pregnancy toxaemia in sheep

Contact Info

Product

Resources

About