Associations of Renal Augmented Velocity Index with Arterial Stiffness, Carotid Intima–Media Thickness and Blood Pressure, in Comparison with Renal Resistive Index

Liu, Kin Hung; Lee, Ming Chung; Kong, Alice Pik Shan; Chen, Ling; Chan, Juliana C.N.

doi:10.1016/j.ultrasmedbio.2021.01.006

Cited by 4 publications

(14 citation statements)

References 24 publications

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“…In this manner, renal Avi was analyzed by means of evaluating its correlation with arterial stiffness and CIMT in comparison to that of renal RI in healthy individuals. Consequently, no correlation of renal Avi with renal RI could be found and renal Avi was shown to be independently associated with age, sex, SBP, DBP, MAP, PP, arterial stiffness, and CIMT while renal RI was found to be in relation with PP only 8 . In accordance with these findings, we revealed that age, SBP, MAP, and PP were correlated with renal Avi while renal Avi was not associated with renal RI or GFR.…”

Section: Discussionsupporting

confidence: 62%

“…Therefore, in agreement with the previous study, we found that GFR was not a predictor of renal RI or renal Avi. And accordingly, we propose that the changes in GFR cannot influence either renal RI or renal Avi when GFR exceeds 90 mL/min/1.73 m 2 reflecting normal renal functions 8 …”

Section: Discussionmentioning

confidence: 98%

“…Peak velocity at late systole ( V L ), early systolic velocity ( V e ), highest systolic velocity ( V h ), and end‐diastolic velocity ( V end ) were analyzed to calculate renal Avi as in the following equation (Figure 4):

Renal Avi = \frac{peak velocity at late systole (V_{L}) - early systolic velocity (V_{e})}{highest systolic velocity (V_{h}) - end ‐ diastolic velocity (V_{end})}

where, V h is described as the higher value of peak velocity between V L and V e 8 …”

Section: Methodsmentioning

confidence: 99%

“…In that pilot study, Avi has been revealed to correlate with various CV risk factors and to be independently associated with arterial stiffness 7 . Just after, Avi has been readily analyzed in renal arteries to evaluate its potential association with CV health in comparison to renal RI and it was documented that renal Avi had associations with blood pressure, arterial stiffness, and carotid intima‐media thickness (CIMT) even stronger than renal RI 8 …”

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confidence: 99%

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The Relationship of Renal Augmented Velocity Index With Ventricular–Arterial Coupling in Comparison to Renal Resistive Index

Karasu

Emekli

2023

J of Ultrasound Medicine

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ObjectiveIt's a well‐known scientific statement that the heart and kidney functions are frequently tied together and the impairment of one directly alters the other. However, there exist knowledge gaps about this intricate pathophysiologic link and the exact unifying mechanism is not established. Herein, we aimed to investigate the presence of cardiorenal interaction at subclinical level while the conventional cardiac and renal clinical parameters are not disrupted yet in patients with hypertension.MethodsWe chose a novel renal Doppler ultrasonographic parameter—augmented velocity index (Avi)—and an echocardiographic measure—ventriculoarterial coupling—which is complex to analyze but increasingly used after its acceptance about being a key determinant of cardiovascular efficiency. We recruited 137 patients without a previous history of antihypertensive medication use (47.4% women; median age, 49 years). Renal Avi, renal resistive index (RI), arterial elastance (Ea), ventricular elastance (Ees) and Ea/Ees (ventriculoarterial coupling) parameters were all examined.ResultsRenal Avi, Ea, and Ea/Ees values were higher in females. Correlation analysis revealed that renal Avi was correlated with many hemodynamic variables including Ea and Ea/Ees. On multiple linear regression analysis, Ea and Ea/Ees remained as significant independent predictors of renal Avi but not of renal RI after adjustments for co‐variables (β = 0.488, P < .001 for Ea; β = 0.380, P < .001 for Ea/Ees).ConclusionsIn comparison to renal RI, we suggest that renal Avi is a more reliable and promising index that can even measure subclinical changes in the cardiorenal circulation which needs to be elucidated.

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Section: Discussionsupporting

confidence: 62%

Section: Discussionmentioning

confidence: 98%

Renal Avi = \frac{peak velocity at late systole (V_{L}) - early systolic velocity (V_{e})}{highest systolic velocity (V_{h}) - end ‐ diastolic velocity (V_{end})}

where, V h is described as the higher value of peak velocity between V L and V e 8 …”

Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 99%

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The Relationship of Renal Augmented Velocity Index With Ventricular–Arterial Coupling in Comparison to Renal Resistive Index

Karasu

Emekli

2023

J of Ultrasound Medicine

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“…A value more than 9.0 is associated with increased RRI and high cardiovascular risk [92]. In addition, in healthy volunteers, Liu et al identified that renal augmented velocity index, a new ultrasound Doppler parameter, has better correlations with pulse pressure, carotid-femoral pulse wave velocity and intima-media thickness in comparison with RRI [93].…”

Section: Renal Resistive Index and The Cardiovascular Systemmentioning

confidence: 99%

Current Insights into Renal Resistive Index Significance in Kidney and Cardiovascular Disease

Darabont¹,

Mihalcea²,

Vinereanu³

2023

Preprint

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Initially, renal resistive index (RRI) was investigated to improve diagnosis in kidney diseases, but failed to meet this goal. Recently many papers highlighted the prognostic significance of RRI in chronic kidney disease, in the estimation of revascularization success of renal artery stenoses or the evolution of the graft and recipients in renal transplantation. Moreover, RRI gained importance in prediction of acute kidney injury in critically ill patients. Along with RRI study in renal pathology have been revealed correlations of this index with parameters of systemic circulation. The theoretical and experimental premises of this connection were reconsidered, and studies for analyzing the link between RRI and arterial stiffness, central and peripheral pressure or left ventricular flow were conducted with this purpose. A high amount of data is currently indicating that RRI is influenced more by pulse pressure and vascular compliance than by renal vascular resistance – assuming that RRI reflects the complex interplay between systemic circulation and renal microcirculation and should be considered as a marker of systemic cardiovascular risk beyond its prognostic relevance for kidney disease. In this review we will go through clinical research that revealed the implications of RRI in renal and cardiovascular disease.

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Sonographic Measurement of Mesenteric Fat Thickness Is a Better Predictor of Aortic Stiffness Compared With Conventional Obesity Indexes

Liu

Kong²,

Chan³

et al. 2023

Ultrasound in Medicine & Biology

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Associations of Renal Augmented Velocity Index with Arterial Stiffness, Carotid Intima–Media Thickness and Blood Pressure, in Comparison with Renal Resistive Index

Cited by 4 publications

References 24 publications

The Relationship of Renal Augmented Velocity Index With Ventricular–Arterial Coupling in Comparison to Renal Resistive Index

The Relationship of Renal Augmented Velocity Index With Ventricular–Arterial Coupling in Comparison to Renal Resistive Index

Current Insights into Renal Resistive Index Significance in Kidney and Cardiovascular Disease

Sonographic Measurement of Mesenteric Fat Thickness Is a Better Predictor of Aortic Stiffness Compared With Conventional Obesity Indexes

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