Associations of serum zinc, copper, and selenium with sleep disorders in the American adults: Data from NHANES 2011–2016

Deng, Ming-Gang; Liu, Fang; Liang, Yuehui; Chen, Yanling; Nie, Jiaqi; Chai, Chee‐Yin; Wang, Kai

doi:10.1016/j.jad.2022.11.088

Cited by 27 publications

(13 citation statements)

References 57 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Furthermore, the restricted cubic spline (RCS) models were utilized to examine the dose-response relationships between dietary carotenoid intakes and sleep duration, with three knots located at the 5th, 50th, and 95th percentiles of the distributions [24,25] . For more visual purposes, we illustrated the levels of dietary carotenoid intakes in participants with different sleep durations, with sleep duration (continuous, h/night) on the X-axis [14] .…”

Section: Discussionmentioning

confidence: 99%

Relationship between dietary carotenoid intake and sleep duration in American adults: A population-based study

Deng,

Liu,

Wang

et al. 2023

Preprint

Self Cite

View full text Add to dashboard Cite

Objective To investigate the relationship between dietary carotenoid intake and sleep duration. Methods Adults enrolled in the National Health and Nutrition Examination Survey (NHANES) 2007–2018 without missing information on dietary carotenoid intake (α-carotene, β-carotene, β-cryptoxanthin, lycopene, and lutein + zeaxanthin), sleep duration, and covariates were included. Participants’ carotenoid consumption was divided into three groups by quartiles and sleep duration was grouped as short (< 7 h/night), optimal (7–8 h/night), and long (> 8 h/night). Multinominal logistic regression was constructed to examine the association between dietary carotenoid intake and sleep duration. Restricted cubic spline (RCS) regression was further utilized to explore their dose-response relationship. The weighted quantile sum (WQS) model was adopted to calculate the mixed and individual effect of 5 carotenoid sub-types on sleep duration. Results Multinominal logistic regression presented that people with higher intakes of α-carotene, β-carotene, β-cryptoxanthin, lycopene, and lutein + zeaxanthin were less likely to sleep too short or too long. Consistent with the findings from multinominal logistic regression, the RCS models suggested a reverse U-shaped relationship between sleep duration and carotenoid intakes. The mixed effects were also significant, where lutein + zeaxanthin and β-cryptoxanthin, α-carotene and β-cryptoxanthin were the top 2 contributors associated with the decreased risks of short and long sleep duration, respectively. Conclusion People with higher carotenoid intakes were more likely to keep an optimal sleep duration, and targeted supplements may be helpful for short and long-sleepers.

show abstract

Section: Discussionmentioning

confidence: 99%

Relationship between dietary carotenoid intake and sleep duration in American adults: A population-based study

Deng,

Liu,

Wang

et al. 2023

Preprint

Self Cite

View full text Add to dashboard Cite

show abstract

“…Furthermore, the restricted cubic spline (RCS) models were utilized to examine the dose-response relationships between dietary carotenoid intakes and sleep duration, with three knots located at the 5 th , 50 th , and 95 th percentiles of the distributions [25,26]. For more visual purposes, we illustrated the levels of dietary carotenoid intakes in participants with different sleep durations, with sleep duration (continuous, h/night) on the X-axis [5].…”

Section: Discussionmentioning

confidence: 99%

Relationship between dietary carotenoid intake and sleep duration in American adults: A population-based study

Deng,

Liu,

Wang

et al. 2023

Preprint

View full text Add to dashboard Cite

Objective: To investigate the relationship between dietary carotenoid intake and sleep duration. Methods: Adults enrolled in the National Health and Nutrition Examination Survey (NHANES) 2007-2018 without missing information on dietary carotenoid intake (α-carotene, β-carotene, β-cryptoxanthin, lycopene, and lutein + zeaxanthin), sleep duration, and covariates were included. Participants’ carotenoid consumption was divided into three groups by quartiles and sleep duration was grouped as short (<7 h/night), optimal (7-8 h/night), and long (>8 h/night). Multinominal logistic regression was constructed to examine the association between dietary carotenoid intake and sleep duration. Restricted cubic spline (RCS) regression was further utilized to explore their dose-response relationship. The weighted quantile sum (WQS) model was adopted to calculate the mixed and individual effect of 5 carotenoid sub-types on sleep duration. Results: Multinominal logistic regression presented that people with higher intakes of α-carotene, β-carotene, β-cryptoxanthin, lycopene, and lutein + zeaxanthin were less likely to sleep too short or too long. Consistent with the findings from multinominal logistic regression, the RCS models suggested a reverse U-shaped relationship between sleep duration and carotenoid intakes. The mixed effects were also significant, where β-cryptoxanthin and lutein + zeaxanthin were the top 2 contributors associated with the decreased risks of short sleep duration, while β-carotene, α-carotene, and β-cryptoxanthin were the main factors related to the lower risk of long sleep duration. Conclusion: Our study revealed that the American adults with optimal sleep duration were associated with more dietary carotenoid intake, in comparison to short or long sleepers.

show abstract

“…Based on previously published research, potential covariates associated with CRDs have been identi ed [49][50][51][52][53]. The presence of mediating effects among these covariates was evaluated using the method proposed by Baron and Kenny [54].…”

Section: Covariatesmentioning

confidence: 99%

“…The sociodemographic variables included age categories (20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35)(36)(37)(38)(39)(40)(41)(42)(43)(44)(45)(46)(47)(48)(49)(50)(51)(52)(53)(54)(55)(56)(57)(58)(59), and 60 years and older), gender (female and male), racial groups (Non-Hispanic White, Mexican American, Non-Hispanic Black, and Other/Multiracial), marital status (Married, Widowed, Divorced, Separated, Never married, and Living with partner), levels of educational attainment (below high school graduate, high school graduate or equivalent, and some college education or higher), and tiers of family income (0-130% of the Federal Poverty Level (FPL), 131-350% of the FPL, and above 350% of the FPL, where FPL is de ned as the family income to poverty threshold ratio). Behavioral characteristics were delineated by smoking status (Individuals with a lifetime consumption of 100 or more cigarettes were classi ed as smokers, with the designation being recorded as either 'yes' or 'no'), alcohol consumption (no or yes), and physical activity levels (inactive or active).…”

Section: Covariatesmentioning

confidence: 99%

Associations of serum Cu, Zn, and Se with Chronic Respiratory Diseases in the American adults: Data from NHANES 2013–2016 and a bidirectional Mendelian randomization analysis

Yu,

LV,

et al. 2024

Preprint

View full text Add to dashboard Cite

Background Despite studies on trace metals and Chronic Respiratory Diseases (CRDs), their causal relationship in American adults is uncertain. Our research applied observational and bidirectional Mendelian randomization (MR) methods to ascertain this association. Objective The aim of this study was to evaluate the potential linkages between serum levels of copper (Cu), zinc (Zn), and selenium (Se) and the incidence of chronic respiratory diseases within the adult demographic of the United States. Methods Drawing on the National Health and Nutrition Examination Survey (NHANES) 2013–2016 data, our study incorporated 2807 adults to examine serum Cu, Zn, and Se impacts on CRDs risks using logistic regression and cubic spline analysis. Subsequently, bidirectional MR assessments were conducted to ascertain the causative linkages pertaining to these associations. Results Employing adjusted-weighted logistic models, high serum Cu significantly escalated the risks for emphysema (OR: 3.83) and Chronic obstructive pulmonary disease (COPD) (OR: 2.14–3.33), while elevated Cu and Zn levels corresponded to respective OR of 1.82 and 1.91 for chronic tracheitis and COPD. Conversely, moderate Se reduced tracheitis risk (OR: 0.64). MR indicated no genetic causation between Cu and respiratory diseases (p > 0.05), yet Cu exposure was causally linked to COPD (p = 0.003), as was Zn (p = 0.014). selenium’s protective genetic association with chronic tracheitis was confirmed (p = 0.010). Conclusion High serum Cu links to increased emphysema, tracheitis, and COPD risk; Zn equally raises COPD risk; Se may lessen tracheitis risk. This observation warrants confirmation through additional large-scale, prospective cohort studies with sufficient sample sizes and extended follow-up durations.

show abstract

Associations of serum zinc, copper, and selenium with sleep disorders in the American adults: Data from NHANES 2011–2016

Cited by 27 publications

References 57 publications

Relationship between dietary carotenoid intake and sleep duration in American adults: A population-based study

Relationship between dietary carotenoid intake and sleep duration in American adults: A population-based study

Relationship between dietary carotenoid intake and sleep duration in American adults: A population-based study

Associations of serum Cu, Zn, and Se with Chronic Respiratory Diseases in the American adults: Data from NHANES 2013–2016 and a bidirectional Mendelian randomization analysis

Contact Info

Product

Resources

About