Associations of vitamin C status, fruit and vegetable intakes, and markers of inflammation and hemostasis

Abstract

The findings suggest that vitamin C has antiinflammatory effects and is associated with lower endothelial dysfunction in men with no history of cardiovascular disease or diabetes.

Low muscle mass in older men: The role of lifestyle, diet and cardiovascular risk factors

“…this is consistent with other studies (34,35) and a review suggesting sarcopenia is a low-level inflammatory state driven by cytokines and oxidative stress (11). these findings highlight the importance of reducing inflammation in older adults, potentially through lifestyle modifications such as increasing physical activity or an anti-inflammatory diet, especially since inflammatory markers increase with age (22,36). Associations between vWF and t-PA with low muscle mass were novel and consistent with a review suggesting that endothelial dysfunction may contribute to sarcopenia development (12).…”

“…Participants reported usual frequency of consumption of 86 food and drink types. nutrient intakes were derived using a validated computer program to calculate total nutrient composition of foods consumed (22). in addition, participants were asked to indicate how often they consumed fresh fruit and vegetables -rarely/never, monthly, or 1, 2, 3, 4, 5, 6, or 7 days per week.…”

“…the multivariate nutrient density model was used to adjust macronutrients for energy intake; carbohydrates, fats and protein were expressed as percentages of energy (% kcal) and energy intake was added to the logistic regression models for all dietary variables (23). Plasma vitamin c and e were also measured using high-performance liquid chromatography (22).…”

“…Metabolic syndrome was classified according to the national cholesterol education Program definition (26); ≥3 metabolic risk factors as follows: 1) central obesity: waist circumference >102 cm; 2) Fasting plasma glucose >6.1mmol/L; 3) serum triglyceride >1.7 mmol/L; 4) serum high density lipoprotein (HDL) cholesterol <1.04 mmol/L; and 5) Hypertension: blood pressure >130/85mmHg or using blood pressure medication. Plasma concentrations of c-reactive protein (cRP), tissue plasminogen activator (t-PA) antigen, D-dimer, von Willebrand factor (vWF), fibrinogen, interleukin 6 (iL-6) and homocysteine were measured as described previously (22,27,28).…”

El Consumo De Frutas Y Hortalizas Ayuda a Prevenir El Daño Endotelial

“…Por otra parte, la vitamina C también previene la apoptosis de las CE inhibiendo intracelularmente la caspasa 9 y la función de ET-1, e impidiendo la liberación de IL-6 (114,115). En un estudio prospectivo, 3258 varones de 60-79 años (sin diagnóstico de infarto de miocardio, ictus o diabetes), se observó que los niveles plasmáticos de vitamina C se relacionaron inversamente con los niveles de PCR-us y del tPA (116). Otro estudio, aleatorizado, doble ciego y controlado con placebo, se demostró que el consumo de vitamina C y E favorece la vasodilatación dependiente del endotelio en pacientes hipertensos esenciales no tratados (117).…”