The monitoring of buildings and structures condition, as well as the timely implementation of corrective actions aimed at the elimination of adverse factors, are the most important aspects that shall be addressed at the construction stage. The usage of monitoring systems makes it possible to monitor the building condition and above that to implement more efficient design solutions in the prospective projects using the results of the analysis of the acquired and design data. In this work the review of a monitoring system installed in a high-rise building located in Ekaterinburg is given. The paper describes the analysis of the natural oscillation frequency and the logarithmic decrement of fundamental tone acquired with the help of accelerometers, and compares the values with the acceptance limits. The process of converting data acquired by strain gauges for the determination of the stress-strain condition of the bearing structures is analysed. The process of comparison of data obtained by the monitoring system of a high-rise building is described. The necessity of the application of the monitoring system is analysed.