Astaxanthin improved the storage stability of docosahexaenoic acid-enriched eggs by inhibiting oxidation of non-esterified poly-unsaturated fatty acids

Wang, Hao; He, Weizhao; Dansou, Dieudonné M.; Zhang, Huiyan; Nugroho, Ramdhan Dwi; Tang, Chaohua; Guo, Xiaoqing; Yu, Yanan; Zhao, Qingyu; Qin, Yuchang; Zhang, Junmin

doi:10.1016/j.foodchem.2022.132256

Cited by 22 publications

(7 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Asta contains a β-ionone ring and a polyunsaturated conjugated double bond system. Thus, it has the ability to quench singlet oxygen and is an excellent scavenger of reactive oxygen species (ROS) [ 11 , 12 ]. The biological activity of Asta is usually related to the reduction of oxidative damage markers, and the production of inflammation is strongly related to oxidative stress.…”

Section: Introductionmentioning

confidence: 99%

In-Depth Analysis of the Mechanism of Astaxanthin Succinate Diester in Reducing Ulcerative Colitis in C57BL/6J Mice Based on Microbiota Informatics

Qiao,

Gao,

Yang

et al. 2023

Molecules

View full text Add to dashboard Cite

This paper aims to explore the effect and mechanism of water-soluble astaxanthin succinate diester (Asta-SD) on ulcerative colitis (UC) induced by dextran sodium sulfate in zebrafish and C57BL/6J mice. Asta-SD was synthesized with hydrophilic fatty acid succinic anhydride and the hydroxyl groups at the ends of F-Asta were synthesized by esterifying. Through the construction of a zebrafish intestinal inflammation model, it was found that Asta-SD could effectively reduce the levels of ROS and increase the number of healthy intestinal lysosomes in zebrafish. After continuous gavage of Asta-SD for seven days, the body weight, disease activity index, colonic length, colonic histopathology, expression of inflammatory factors, and intestinal flora of the mice were measured. The results showed that Asta-SD could significantly alleviate weight loss and colonic shrinkage, as well as reducing pro-inflammatory cytokines and recess injury in UC mice. The 16S rRNA gene sequencing showed that Asta-SD significantly increased the beneficial bacteria (Lactobacillus, Anaerotruncus) and decreased the relative abundance of pathogenic bacteria, effectively maintaining intestinal microbiota homeostasis in mice. Based on Pearson analysis, Bacteroides, Parabacteroides, and Butyrimionas were expected to be associated with the significant difference in the expression of inflammatory factors between the UC and the corresponding host. Thus, Asta-SD significantly improves UC and maintains intestinal microbiota homeostasis.

show abstract

Section: Introductionmentioning

confidence: 99%

In-Depth Analysis of the Mechanism of Astaxanthin Succinate Diester in Reducing Ulcerative Colitis in C57BL/6J Mice Based on Microbiota Informatics

Qiao,

Gao,

Yang

et al. 2023

Molecules

View full text Add to dashboard Cite

show abstract

“…was distributed in deep‐water layers with low UVR during the day, astaxanthin may not be used to mitigate the oxidative damage caused by high levels of UVR, possibly being replaced to protect fatty acids from oxidation. Under natural conditions, copepods can inhibit the oxidation of PUFAs by accumulating astaxanthin, which is conducive to fatty acid storage as described in previous studies (Schneider et al, 2016, 2017; Sommer et al, 2006; Wang et al, 2022). PUFAs in algae were found to influence the food quality of herbivorous zooplankton (Ravet & Brett, 2003; Weers & Gulati, 1997), especially at low temperatures.…”

Section: Discussionmentioning

confidence: 57%

Upward migration of calanoid copepods is driven by high food quality in surface waters in an alpine lake

Cui,

Ding,

Wang

et al. 2023

Freshwater Biology

View full text Add to dashboard Cite

The diel vertical migration of zooplankton includes downward migration to deep water during the day and upward migration to surface water at night. Diurnal downward migration has been well explained; zooplankton migration to surface water at night remains unclear. This study aimed to explore the reason of the nocturnal upward migration of the calanoid copepod Arctodiaptomus sp. In Lake Heihai, an alpine lake (elevation 4,090 m above sea level) without predators. Herein, we present the vertical profiles of the lake, including water temperature, chlorophyll a (Chl‐a), fatty acids, and astaxanthin synthesis precursors (ASPs) of seston in the water column. The distributions and concentrations of fatty acids and astaxanthin in Arctodiaptomus sp. were characterised through field investigations during the day and at night. Meanwhile, the effect of ultraviolet radiation (UVR) on ASPs in seston was explored through indoor experiments. Lake Heihai had the characteristics of low temperature, low food availability, high transparency, and high UVR intensity. Arctodiaptomus sp. was distributed in water layers below 6 m during the day and throughout the water column at night. Arctodiaptomus sp. accumulated large amounts of fatty acids, especially polyunsaturated fatty acids (PUFAs), and inhibitors of fatty acid oxidation–astaxanthin in the cold alpine lake. The concentrations of lutein, a kind of ASP, and PUFAs in seston were highest in surface waters. The indoor experiment verified that UVR can enhance the synthesis of ASP. The calanoids migrated to surface waters at night to obtain ASPs and PUFAs in seston, which were at high concentrations in surface waters. PUFAs and ASP may be of high food quality for zooplankton in alpine lakes. The findings indicated that the upward migration of Arctodiaptomus sp. at night was driven by the high quality of food sources (PUFAs and ASP) in surface waters. Arctodiaptomus sp. adapts behaviour and physiology to the environment of the alpine lake. We explored why zooplankton migrated to surface waters at night from the perspective of their physiological characteristics and adaptability to the environment. Our findings provide a new way to investigate the diel vertical migration of zooplankton, especially in alpine lakes.

show abstract

“…However, not all research results showed competition between carotenoids in animals, Zhao et al demonstrated that the deposition of astaxanthin in egg yolks might lower the content of lutein, whereas it did not affect zeaxanthin ( Zhao et al, 2023 ). Another study also showed that the enrichment of astaxanthin in egg yolks did not significantly affect the zeaxanthin content ( Wang et al, 2022 ). In an in vitro experiment using caco-2 cells to investigate the competitions between carotenoids for their uptake, the results showed that lutein uptake was not significantly affected by the addition of phytoene and phytofluene.…”

Section: Metabolic Pathways Of Carotenoids In Animalsmentioning

confidence: 99%

Deposition and enrichment of carotenoids in livestock products: An overview

Miao,

Si,

Zhao

et al. 2024

Food Chemistry: X

Self Cite

View full text Add to dashboard Cite

Astaxanthin improved the storage stability of docosahexaenoic acid-enriched eggs by inhibiting oxidation of non-esterified poly-unsaturated fatty acids

Cited by 22 publications

References 40 publications

In-Depth Analysis of the Mechanism of Astaxanthin Succinate Diester in Reducing Ulcerative Colitis in C57BL/6J Mice Based on Microbiota Informatics

In-Depth Analysis of the Mechanism of Astaxanthin Succinate Diester in Reducing Ulcerative Colitis in C57BL/6J Mice Based on Microbiota Informatics

Upward migration of calanoid copepods is driven by high food quality in surface waters in an alpine lake

Deposition and enrichment of carotenoids in livestock products: An overview

Contact Info

Product

Resources

About