Asthma, allergy, mood disorders, and nutrition

Abstract

BackgroundGrowing evidence supports comorbidity of asthma and allergies with mood disorders and various connections between these diseases. It still remains unclear whether this comorbidity is caused by the same pathophysiological factors or whether there are other links between asthma and depression. There is no definite answer to the question of an optimal treatment to deal with both asthma and depression, when they occur simultaneously. Epidemiological and clinical trials on the influence of nutrition on certain diseases suggest the effects of ω3 polyunsaturated fatty acids (PUFAs) in aiding treatment of mood disorders and inflammatory conditions.ObjectiveThis is an overview showing the connections between asthma, allergic disease, and mood disorders, and the influence of nutrition on these conditions. Evidence indicates positive correlations between consumption of PUFAs and mood correction. Several analyses show the connection between diet and asthma. They may form a basis for potential recommending ω3 PUFAs as an adjuvant in prevention and treatment of mental disorders, asthma, and allergy.

Chronic Critical Illness and PICS Nutritional Strategies

“…While uncertainty may exist on which lipid formulation to deliver, there is no debate regarding the need to meet the essential FA and cellular oxidative requirements. The beneficial anti-inflammatory effects of omega 3 FAs (primarily eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)) have been well documented in several chronic inflammatory diseases, including rheumatoid arthritis, Crohn’s disease, ulcerative colitis, lupus, multiple sclerosis, and asthma [ 81 , 82 , 83 , 84 , 85 ]. Recent evidence from an updated meta-analysis by Pradelli et al suggests a similar benefit with omega 3 supplementation.…”

Why context matters when changing the diet: A narrative review of placebo, nocebo, and psychosocial context effects and implications for outcome research and nutrition counselling

“…These and possibly other character traits [e.g., openness to new experiences, extraversion; ( 87 )] may therefore cause PE and NE in diet changes. In addition, it appears plausible that mental vulnerabilities as for example high anxiety scores ( 88 , 89 ) may lead to NE, especially in view of studies testing diet changes in persons with chronic diseases, allergies, or food intolerances ( 90 ). Anxiety may also play a role in decisions for or against food supplements or a diet change (e.g., vitamin B12 for vegans), in particular where children and adolescents or pregnant women are concerned.…”

Nutritional and Metabolic Therapy

“…104,105 The heterogeneous nature of the ICU population makes lipid administration in these groups somewhat challenging. [107][108][109][110] In addition to the use of antiinflammatory lipids in the setting of chronic illness, the use of specific antiinflammatory lipid substrates in the acute hyperdynamic setting to maintain vital organ function and to modulate key processes such as immunity, inflammation, and antioxidant defenses has now become routine in many surgical and ICU settings. The use of lipids in this manner replaces malabsorbed lipid nutrients and serves as a daily source of calories shown to be equally nitrogen-sparing with glucose when administered continuously for 4 days.…”