Asthma and mental health among youth: etiology, current knowledge and future directions

Goodwin, Renée D.; Bandiera, Frank C.; Steinberg, Dara M.; Ortega, Alexander N.; Feldman, Jonathan

doi:10.1586/ers.12.34

Cited by 61 publications

(41 citation statements)

References 100 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Conversely, happiness affects autonomic patterns that may relieve airway constriction (41). It has also been suggested that the association between depression and incident asthma may be explained by either a shared comorbidity, such as obesity, or a shared environmental exposure, such as cigarette smoking (19,42). These explanations, however, are unlikely, as our findings persist when the analysis is limited to nonobese participants or when BMI and/or smoking are included as covariates in our multivariable analyses.…”

Section: Discussionmentioning

confidence: 66%

Depression and Risk of Incident Asthma in Adults. The CARDIA Study

Brunner

Schreiner

Sood

et al. 2014

Am J Respir Crit Care Med

View full text Add to dashboard Cite

Rationale: Asthma is associated with depression, but the temporality of the association has not been established.Objectives: To examine the association between prevalent elevated depressive symptoms and incident asthma, and between prevalent asthma and incident elevated depressive symptoms in a cohort of young and middle-aged adults.Methods: We examined the longitudinal association between asthma and depressive symptoms bidirectionally in the Coronary Artery Risk Development in Young Adults (CARDIA) cohort. First, 3,614 participants, free of asthma, were classified by elevated depressive symptoms at the CARDIA Year-5 exam (n = 856 elevated vs. 2,758 not elevated; ages 23-35 yr) and followed for 20 years to incident asthma. Then, 3,016 participants, free of elevated depressive symptoms, were classified by self-reported current asthma status (n = 188 prevalent vs. 2,828 not prevalent) at the CARDIA Year-5 exam and followed for 20 years until onset of elevated depressive symptoms. Measurements and Main Results:The relative hazard of incident asthma among those with elevated depressive symptoms was 1.26 (95% confidence interval [CI] = 1.02-1.56) after adjustment for covariates. When depressive status was modeled as the total number of reports of elevated depressive symptoms before the onset of asthma, the adjusted hazard ratio was 1.15 (95% CI = 1.02-1.29). The hazard of incident elevated depressive symptoms for those with asthma was no different than the hazard in those without asthma (adjusted hazard ratio = 0.92; 95% CI = 0.70-1.20).Conclusions: This longitudinal observational study points to depression as a marker of risk for incident adult-onset asthma. On the other hand, prevalent asthma is not associated with incident adultonset depression.

show abstract

Section: Discussionmentioning

confidence: 66%

Depression and Risk of Incident Asthma in Adults. The CARDIA Study

Brunner

Schreiner

Sood

et al. 2014

Am J Respir Crit Care Med

View full text Add to dashboard Cite

show abstract

“…This indicates that adaptation to the illness among patients with CKD is partially successful. Other authors indicated a significantly higher level of anxiety among children with such diseases as asthma, diabetes or epilepsy, may lead to a medical crisis and also make a child more anxious about being away from their caregivers [29,30]. Although some studies have failed to find a link between asthma and depression in children [31.…”

Section: Discussionmentioning

confidence: 99%

Anxiety in Children and Adolescents with Chronic Kidney Disease - Multicenter National Study Results

Kiliś‐Pstrusińska

Medyńska

Adamczak³

et al. 2013

Kidney Blood Press Res

View full text Add to dashboard Cite

Background/Aims: Chronic medical illness is a significant risk factor for the development of psychiatric disorders. The aims of the study were: to investigate the level of anxiety in children with chronic kidney disease (CKD) and to identify factors associated with the presence of that emotional problem. Methods: CKD children on hemodialysis (HD, n=22), peritoneal dialysis (PD, n=20,) and on conservative treatment (CT, n=95) were enrolled in the study. We used State-Trait Anxiety Inventory (STAI) for adolescents and STAI-C for children. Socio-demographic and physical factors were assessed. Results: There was a significantly higher level of anxiety-state among HD children (8-12 years) compared with other groups of participants of the same age and Polish population norms. The level of anxiety among adolescents (13-18 years), both anxiety-state and anxiety-trait, was significantly higher in the HD group compared with other groups, which did not differ among themselves. In the HD adolescents, there was a correlation between the anxiety-state and the duration of the disease as well as with the number of hospitalizations. PD adolescents in the mainstream education had higher levels of anxiety-state and anxiety-trait compared with home schooled patients. Conclusions: Even though children and adolescents with CKD are at risk of developing a variety of emotional disorders, the level of anxiety among the researched group, with the exception of HD patients, was not significantly different than the level of anxiety among healthy subjects. Adolescents on HD who present a high level of anxiety should undergo long-term psychological treatment.

show abstract

“…Mechanism-wise, other psychobiological pathways may be involved, such as the autonomic nervous system. We know from asthma literature that depression is M A N U S C R I P T A C C E P T E D ACCEPTED MANUSCRIPT associated with increased vagally-mediated airways responses (36), typically coinciding with sympathetic dominance at other organ sites, such as the heart, owing to the directional fractionation of autonomic nervous system activity between organ sites. Future research should replicate the current findings and investigate psychobiological pathways between emotional distress and dyspnea and lung function in patients with HF.…”

Section: Accepted Manuscriptmentioning

confidence: 99%