Asthma control in adults

Rees, John

doi:10.1136/bmj.332.7544.767

Cited by 28 publications

(13 citation statements)

References 30 publications

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“…Asthma exacerbation; hyperreaction of airways to environmental allergens or irritants, is considered as epiphenomenon of poor control asthma [59,60]. Increasing incidence of asthma exacerbation is consequence of two major factors: deficiency in therapy, or poor management of asthma.…”

Section: Asthma Exacerbationmentioning

confidence: 99%

Application of Intelligent Systems in Asthma Disease: Designing a Fuzzy Rule-Based System for Evaluating Level of Asthma Exacerbation

2011

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This paper discusses the capacities of artificial intelligence in the process of asthma diagnosing and asthma treatment. Developed intelligent systems for asthma disease have been classified in five categories including diagnosing, evaluating, management, communicative facilities, and prediction. Considering inputs, results, and methodologies of the systems show that by focusing on meticulous analysis of quality of life as an input variable and developing patient-based systems, under-diagnosing and asthma morbidity and mortality would decrease significantly. Regard to the importance of accurate evaluation in accurate prescription and expeditious treatment, the methodology of developing a fuzzy expert system for evaluating level of asthma exacerbation is presented in this paper too. The performance of this system has been tested in Asthma, Allergy, and Immunology Center of Iran using 25 asthmatic patients. Comparison between system's results and physicians' evaluations using Kappa coefficient (K) reinforces the value of K = 1. In addition this system assigns a degree in gradation (0-10) to every patient representing the slight differences between patients assigned to a specific category.

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Section: Asthma Exacerbationmentioning

confidence: 99%

Application of Intelligent Systems in Asthma Disease: Designing a Fuzzy Rule-Based System for Evaluating Level of Asthma Exacerbation

2011

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“…The economic burden in terms of direct (hospitalization, use of emergency room visits, therapy) and indirect (missed days of work/school) costs adds to the emotional, physical and social impact of asthma, with consequent quality of life deterioration for both patients and their families [3]. Despite the availability of effective treatments, a large proportion of asthma patients experience symptoms of uncontrolled asthma, even in those geographical areas where good standards of care are available [2,[4][5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Fluticasone propionate/formoterol: A fixed-combination therapy with flexible dosage

Papi

Blasi

Canonica

et al. 2014

European Journal of Internal Medicine

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International guidelines describe asthma control as the main outcome of asthma management. Prevention of symptoms, improved quality of life, and reduction of exacerbations are the main components, consequently decreasing health care costs. However, many of these objectives remain unmet in real life: several surveys show that a large proportion of asthmatic patients are not well controlled despite the efficacy of current available treatment. Several randomized controlled clinical trials indicate that combining inhaled corticosteroids and long-acting β 2 -agonists, by means of a single inhaler, greatly improves the management of the disease. The results of 9 multicenter phase III clinical studies demonstrate that the fixed combination of fluticasone propionate/formoterol in a single inhaler is effective in terms of lung function and symptom control. These studies highlight the dose flexibility, safety and tolerability of this new inhaled combination. These characteristics meet the recommendations of international guidelines, and the preferences of respiratory physicians who identified these aspects as critical components of a successful asthma therapy. Combination of fluticasone propionate/formoterol in a single inhaler provides potent anti-inflammatory activity of fluticasone propionate and rapid onset of action of the β 2 -agonist formoterol making this association a viable treatment option both in terms of effectiveness and compliance.

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“…3,4 In daily clinical practice, asthma treatment decisions are usually based on patient-reported symptoms and simple measures of lung function. Since…”

Section: Introductionmentioning

confidence: 99%

Development of a questionnaire for the assessment of bronchial hyperresponsiveness

Postma

Kerstjens

et al. 2009

Primary Care Respiratory Journal

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Asthma control in adults

Cited by 28 publications

References 30 publications

Application of Intelligent Systems in Asthma Disease: Designing a Fuzzy Rule-Based System for Evaluating Level of Asthma Exacerbation

Application of Intelligent Systems in Asthma Disease: Designing a Fuzzy Rule-Based System for Evaluating Level of Asthma Exacerbation

Fluticasone propionate/formoterol: A fixed-combination therapy with flexible dosage

Development of a questionnaire for the assessment of bronchial hyperresponsiveness

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