Asthma control in Latin America: The Asthma Insights and Reality in Latin America survey (AIRLA)

Neffen, Hugo; Fritscher, Carlos Cézar; Schacht, Francisco Cuevas; Soriano, JB; Mechali, D.

doi:10.1016/j.jaci.2004.12.703

Cited by 35 publications

(42 citation statements)

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“…These data are in agreement with those obtained in previous studies conducted in Europe and Latin America. (21,22) Our data regarding ICU admissions and in-hospital deaths are consistent with previous findings. (7) In the present study, 6.7% of all hospitalized asthma patients required ICU admission, and the mortality rate among patients admitted to the ICU was 8.3%.…”

Section: Discussionsupporting

confidence: 91%

The study of severe asthma in Latin America and Spain (1994-2004): characteristics of patients hospitalized with acute severe asthma

et al. 2009

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Objective: Studies assessing the characteristics and management of patients hospitalized with asthma have been limited to a small number of facilities and have evaluated short time periods. The present study evaluated long-term changes among hospitalized asthma patients at a large number of facilities. Methods: This was a retrospective, hospital-based observational case series, designated the Study of Severe Asthma in Latin America and Spain, which was conducted in Spain and in eight Latin-American countries. We reviewed the hospital records of 3,038 patients (age range, 15-69 years) hospitalized with acute severe asthma at one of nineteen tertiary-care hospitals in 1994, 1999 and 2004. Results: Over time, the use of inhaled corticosteroids and long-acting β 2 agonists increased significantly, whereas the use of theophylline as a controller medication decreased. The utilization of pulmonary function tests also increased. There was a significant reduction in the mean hospital stay (8.5 days, 7.4 days and 7.1 days in 1994, 1999 and 2004, respectively, p = 0.0001) and a significant increase in the mean of the lowest arterial pH at hospital admission. In contrast, there was a significant decrease in the proportion of cases in which PEF was determined in the emergency room (48.6% in 1994 vs. 43.5% in 2004, p = 0.0001). We found the quality of asthma management and care to be generally better in Spain than in Latin America. Conclusions: Although there have been certain improvements in the management of asthma between severe exacerbations and during hospitalization, asthma management remains suboptimal in Spain and, especially, in Latin America.Keywords: Status asthmaticus; Asthma/therapy; Hospitalization. ResumoObjetivo: Estudos que avaliem as características e o gerenciamento de pacientes asmáticos hospitalizados têm sido limitados a um número pequeno de serviços e a curtos períodos de duração. O presente estudo avaliou alterações de longo prazo de pacientes asmáticos hospitalizados em um grande número de serviços. Métodos: Estudo retrospectivo, observacional, de base hospitalar, denominado Estudo sobre Asma Grave na América Latina e Espanha, realizado na Espanha e em oito países da América Latina. Foi realizada uma revisão dos registros hospitalares de 3.038 pacientes (variação de idade, 15-69 anos) hospitalizados com asma aguda grave em um dos 19 hospitais terciários em 1994, 1999 e 2004. Resultados: Ao longo do tempo, o uso de corticosteroides inalatórios e de β 2 -agonistas aumentou significativamente, ao passo que o uso de teofilina, como medicação de controle, decaiu. A utilização de testes de função pulmonar também aumentou. Houve uma redução significativa da média do tempo de internação (8,5 dias, 7,4 dias e 7,1 dias em 1994, 1999 e 2004, respectivamente; p = 0,0001) e um aumento significativo da média do menor pH arterial na admissão. Em contrapartida, houve uma diminuição significativa na proporção de casos submetidos ao PFE no pronto-socorro (48,6% em 1994 vs. 43,5% em 2004; p = 0,0001).O tratamen...

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Section: Discussionsupporting

confidence: 91%

The study of severe asthma in Latin America and Spain (1994-2004): characteristics of patients hospitalized with acute severe asthma

et al. 2009

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“…Previous publications estimate that families spending 50% or more of their nonfood expenditure fit in this category (17,18). Recent surveys have shown that the proportion of individuals with persistent asthma reporting use of inhaled corticosteroids (ICS), the cornerstone of treatment, is very low in various continents (19)(20)(21). The cost of regular treatment is unaffordable to families in low-resource settings (9), resulting in considerable higher proportion of uncontrolled asthma, which is associated with greater economic burden to families and health systems, loss of productivity and deterioration in quality of life (22).…”

Section: The Unbearable Cost Of Severe Asthma In Underprivileged Popumentioning

confidence: 99%

The unbearable cost of severe asthma in underprivileged populations

Cruz

Bousquet

2009

Allergy

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“…According to data of population-based surveys there is a gap between asthma management as stipulated by GINA and the achievement of asthma control around the world (2)(3)(4)(5)(6). These studies have shown high levels of both emergency room visits and hospitalization despite the availability of effective therapies to achieve asthma control.…”

Section: Introductionmentioning

confidence: 99%

Direct costs of asthma in Brazil: a comparison between controlled and uncontrolled asthmatic patients

Santos

Oliveira

Faresin

et al. 2007

Braz J Med Biol Res

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Asthma is a common chronic illness that imposes a heavy burden on all aspects of the patient's life, including personal and health care cost expenditures. To analyze the direct cost associated to uncontrolled asthma patients, a cross-sectional study was conducted to determine costs related to patients with uncontrolled and controlled asthma. Uncontrolled patient was defined by daytime symptoms more than twice a week or nocturnal symptoms during two consecutive nights or any limitations of activities, or need for relief rescue medication more than twice a week, and an ACQ score less than 2 points. A questionnaire about direct cost stratification in health services, including emergency room visits, hospitalization, ambulatory visits, and asthma medications prescribed, was applied. Ninety asthma patients were enrolled (45 uncontrolled/45 controlled).

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Asthma control in Latin America: The Asthma Insights and Reality in Latin America survey (AIRLA)

Cited by 35 publications

References 0 publications

The study of severe asthma in Latin America and Spain (1994-2004): characteristics of patients hospitalized with acute severe asthma

The study of severe asthma in Latin America and Spain (1994-2004): characteristics of patients hospitalized with acute severe asthma

The unbearable cost of severe asthma in underprivileged populations

Direct costs of asthma in Brazil: a comparison between controlled and uncontrolled asthmatic patients

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