Asthme et Mycoplasma pneumoniae

Mycoplasma pneumonia infection and asthma: A clinical study

“…A number of respiratory infections have been reported to be involved in the occurrence of asthma, in which mycoplasma pneumonia is an organism having a strong relationship to asthma and reported by many authors. 4 , 7 In the current study, we found that the rate of mycoplasma pneumonia infection was 48.71%in acute asthma group, and 30.98%in convalescent group, demonstrating that the percentage of mycoplasma pneumonia infection in asthma patients was high, which confirmed the previous viewpoints. 4 , 7 At the same time, the infection rate in convalescent group is significantly lower than that in acute asthma group, indicating that the mycoplasma pneumonia infection may play more important role in the occurrence of acute asthma, which is consistant with the points resulted from Zhou’s study.…”

“… 3 The role of respiratory tract infections caused by mycoplasma pneumonia in the pathogenesis of asthma has been well established and physicians suggested mycoplasma pneumonia infection seems to be important in asthma pathogenesis and the clinical course of the disease. 4 In terms of the exact influence of mycoplasma pneumonia on asthma, some authors suggested that mycoplasma pneumonia infection can precede the onset of asthma, exacerbate asthmatic symptoms, and cause difficulties with asthma management. 5 , 6 On the other hand, some authors found that the asthma control status and parameters of lung function tests did not differ between asthmatic patients with and without evidence of mycoplasma pneumonia infection, and advocated that mycoplasma pneumonia infection is not related to asthma control, asthma severity, and location of airway obstruction.…”

Incident asthma and Mycoplasma pneumoniae: A nationwide cohort study

“…6,7 In a previous study the impairment of lung functionality caused by infection at the acute 13,14 or chronic 39 stage was more likely to result from M pneumoniae than from other pulmonary infections. 35 We have found M pneumoniae infection 41,47 contributes to the incident development or progression of early-onset and late-onset asthma, regardless of comorbidities, antibiotic and steroid use, and outpatient and hospitalization status.…”

Intérêt de l’identification en routine des agents pathogènes respiratoires chez les enfants hospitalisés pour une exacerbation d’asthme

“…Dans les différen-tes études épidémiologiques prospectives où des prélève-ments microbiologiques ont été systématiquement réalisés, le VRS et le rhinovirus sont les principaux agents infectieux identifiés lors des exacerbations d'asthme [1,2,9]. Dans l'étude de Freymuth et al [10] [11,17,18], ce qui n'avait été fait dans notre étude que pour 7 enfants. Les autres recherches microbiologiques prescrites durant la période d'étude étaient globalement injustifiées.…”

“…Est-il le plus grand pourvoyeur de primoexacerbation ? Quelle est la stratégie optimale pour l'identifier[3,[11][12][13][14][15] ? Il semble de plus que les méthodes d'identification actuelles ne permettent pas de distinguer un portage sain d'une infection symptomatique[16].…”