Asymmetric patterning drives the folding of a tripodal DNA nanotweezer

Abstract

DNA tweezers have emerged as powerful devices for a wide range of biochemical and sensing applications; however, most DNA tweezers consist of single units activated by DNA recognition, limiting their...

Mechanics of dynamic and deformable DNA nanostructures

“…Since this seminal work, numerous studies have been reported using similar strategies. 105,[131][132][133][134][135][136][137][138][139][140] Another typical example is the DNA box shown in Fig. 5(b).…”

DNA-Mediated Peptide Assembly into Protein Mimics

“…DNA is a biomolecule that exhibits unparalleled programmability and predictability in its assembly, owing to its Watson–Crick-Franklin base-pairing interactions. , With the development of DNA nanotechnology, a number of structural motifs have been generated, such as tiles, − DNA origami, − multiway junctions, − and hybrid DNA–polymer and cage structures. − These can precisely position materials on the nanoscale into arbitrarily designed symmetric or asymmetric patterns. , A DNA scaffold is thus an ideal template for the assembly of peptides with a precise spatial arrangement. Bayley et al have used ring-shaped DNA scaffolds to support the formation of peptide nanopores from identical peptide units .…”

Bubble DNA tweezer: A triple-conformation sensor responsive to concentration-ratios

“…Since its inception, DNA computing 1 has rapidly advanced owing to its specificity and programmability. The introduction of multifunctional DNA structures, including nano-cages, 2 gears, 3 walkers, 4 and tweezers, 5 has enabled breakthroughs in molecular circuits, 6 nanomachines, 7 and molecular signal detection. 8 , 9 Among these, the DNA tweezer structure 10 stands out owing to its flexible opening and closing dynamics.…”