Asymmetric periflexural exanthem of childhood: report of two cases with parvovirus B<sub>19</sub>

Guimerá‐Martín‐Neda, F.; Fagundo, E.; Rodríguez, F; Cabrera, Raimundo; Sánchez, Rosalba; García, Miguel Ángel Serrano; Sáez, Miguel; Noda, Antonio Sedeño

doi:10.1111/j.1468-3083.2006.01443.x

Cited by 28 publications

(12 citation statements)

References 6 publications

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“… 135-160 In most reported patients, no viral cause was identified. 135 , 137 , 138 , 140 , 147 Associated viruses include B19V, 141 , 147 , 154 , 155 parainfluenza virus 2, 147 parainfluenza 3, 147 and adenovirus. 142 However, many reports fall short of having applied sufficient investigations.…”

Section: Asymmetric Periflexural Exanthem/unilateral Laterothoracic Ementioning

confidence: 99%

Pityriasis rosea, Gianotti-Crosti syndrome, asymmetric periflexural exanthem, papular-purpuric gloves and socks syndrome, eruptive pseudoangiomatosis, and eruptive hypomelanosis: do their epidemiological data substantiate infectious etiologies?

Chuh

Zawar²,

Sciallis

et al. 2016

Infectious Disease Reports

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Many clinical and laboratory-based studies have been reported for skin rashes which may be due to viral infections, namely pityriasis rosea (PR), Gianotti-Crosti syndrome (GCS), asymmetric periflexural exanthem/unilateral laterothoracic exanthem (APE/ULE), papular-purpuric gloves and socks syndrome (PPGSS), and eruptive pseudo-angiomatosis (EP). Eruptive hypomelanosis (EH) is a newly discovered paraviral rash. Novel tools are now available to investigate the epidemiology of these rashes. To retrieve epidemiological data of these exanthema and analyze whether such substantiates or refutes infectious etiologies. We searched for articles published over the last 60 years and indexed by PubMed database. We then analyzed them for universality, demography, concurrent patients, temporal and spatial-temporal clustering, mini-epidemics, epidemics, and other clinical and geographical associations. Based on our criteria, we selected 55, 60, 29, 36, 20, and 4 articles for PR, GCS, APE/ULE, PPGSS, EP, and EH respectively. Universality or multiple-continental reports are found for all exanthema except EH. The ages of patients are compatible with infectious causes for PR, GCS, APE/ULE, and EH. Concurrent patients are reported for all. Significant patient clustering is demonstrated for PR and GCS. Mini-epidemics and epidemics have been reported for GCS, EP, and EH. The current epidemiological data supports, to a moderate extent, that PR, GCS, and APE could be caused by infectious agents. Support for PPGSS is marginal. Epidemiological evidences for infectious origins for EP and EH are inadequate. There might be growing epidemiological evidence to substantiate or to refute our findings in the future.

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Section: Asymmetric Periflexural Exanthem/unilateral Laterothoracic Ementioning

confidence: 99%

Pityriasis rosea, Gianotti-Crosti syndrome, asymmetric periflexural exanthem, papular-purpuric gloves and socks syndrome, eruptive pseudoangiomatosis, and eruptive hypomelanosis: do their epidemiological data substantiate infectious etiologies?

Chuh

Zawar²,

Sciallis

et al. 2016

Infectious Disease Reports

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“…Although the eruptions described in these reports were more generalized than in our case, flexural involvement and associated petechiae were noted. Parvovirus B19 has also been reported to cause peri‐flexural petechial eruptions without pustules in adults 7,8 and children 9 …”

Section: Discussionmentioning

confidence: 99%

Parvovirus B19 infection presenting as ‘bathing trunk’ erythema with pustules

2006

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A 7-year-old girl presented with acute vulval erythema and pustules, associated with a petechial eruption in her flexures and over her feet. There was a mild prodromal illness and the patient was afebrile. There were minimal symptoms associated with the rash. Skin and throat swabs were negative and blood examination showed mild neutrophilia and lymphopaenia. Parvovirus B19 IgM was detected on serology and cutaneous features resolved within 4 days. This is a further case of parvovirus B19 infection presenting as a 'bathing trunk' exanthem that has unique dermatologic features, including the presence of pustules and distant petechiae.

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“…Talgdrüsenreiche Areale des Menschen, wie die zentrale Brust-und Rückenregion sowie das Gesicht werden von dem saprophytär lebenden Keim besiedelt. Die Malassezia-Hefen zählen zur physiologischen menschlichen Hautflora, können jedoch verschiedene Hautkrankheiten verursachen [2]. Beim seborrhoischen Ekzem ist eine Assoziation mit Malassezia-Hefen beschrieben, die ätio-logische Bedeutung der Sprosspilze wird jedoch kontrovers diskutiert [3].…”

Section: Diskussionunclassified

“…parainfektiöse Genese, wofür das gelegentlich epidemieartige Auftreten der Erkrankung spricht [4], sowie eine saisonale Häufung im Frühjahr [6]. In Einzelfällen wurden Assoziationen des ULE mit Parvovirus-B19-Infektionen berichtet [2].…”

Section: Diskussionunclassified

Unilaterales laterothorakales Exanthem

et al. 2006

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Asymmetric periflexural exanthem of childhood: report of two cases with parvovirus B₁₉

Cited by 28 publications

References 6 publications

Pityriasis rosea, Gianotti-Crosti syndrome, asymmetric periflexural exanthem, papular-purpuric gloves and socks syndrome, eruptive pseudoangiomatosis, and eruptive hypomelanosis: do their epidemiological data substantiate infectious etiologies?

Pityriasis rosea, Gianotti-Crosti syndrome, asymmetric periflexural exanthem, papular-purpuric gloves and socks syndrome, eruptive pseudoangiomatosis, and eruptive hypomelanosis: do their epidemiological data substantiate infectious etiologies?

Parvovirus B19 infection presenting as ‘bathing trunk’ erythema with pustules

Unilaterales laterothorakales Exanthem

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Asymmetric periflexural exanthem of childhood: report of two cases with parvovirus B19

Cited by 28 publications

References 6 publications

Pityriasis rosea, Gianotti-Crosti syndrome, asymmetric periflexural exanthem, papular-purpuric gloves and socks syndrome, eruptive pseudoangiomatosis, and eruptive hypomelanosis: do their epidemiological data substantiate infectious etiologies?

Pityriasis rosea, Gianotti-Crosti syndrome, asymmetric periflexural exanthem, papular-purpuric gloves and socks syndrome, eruptive pseudoangiomatosis, and eruptive hypomelanosis: do their epidemiological data substantiate infectious etiologies?

Parvovirus B19 infection presenting as ‘bathing trunk’ erythema with pustules

Unilaterales laterothorakales Exanthem

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Product

Resources

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Asymmetric periflexural exanthem of childhood: report of two cases with parvovirus B₁₉