Asymmetry in semicircular canal diameters may account for circling behavior in EphB‐deficient mice

Lee, Kenneth H.; Lee, James; Shao, Dongmei; Dravis, Christopher; Henkemeyer, Mark

doi:10.1002/lary.24506

Cited by 1 publication

(1 citation statement)

References 22 publications

(47 reference statements)

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“…In another study, Lee et al measured the size of the superior semicircular canal in ephrin-binding receptor-deficient mice with vertigo. 23 They discovered that the lumen diameters of the left and right superior semicircular canals were asymmetric and that this was unrelated to the direction of vertigo. In our study, the inner diameters of almost all the semicircular canals of BPPV patients were observed as narrow, regardless of the affected canal.…”

Section: Discussionmentioning

confidence: 99%

Semicircular canals are long in patients with benign paroxysmal positional vertigo

Başkadem Yılmazer,

Bircan,

Erk

et al. 2023

J. Laryngol. Otol.

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Objective To search for any morphological variation contributing to aetiopathogenesis and the diagnosis of benign paroxysmal positional vertigo, we measured the sizes of the semicircular canals in patients with and without benign paroxysmal positional vertigo using multidetector computed tomography. Methods Cranial bone computed tomography images of 30 benign paroxysmal positional vertigo patients and 30 control patients were acquired with a 128-slice computed tomography scanner and a transverse plane with a thickness of 0.67 mm. The inner diameter, height and width of the canals were measured. Results The width of the anterior semicircular canals, and the width and height of the posterior semicircular canals of the affected ears in benign paroxysmal positional vertigo patients (n = 30) were significantly greater than in the control patients (n = 90; p = 0.001, p = 0.023, p = 0.003, respectively). Conclusion In benign paroxysmal positional vertigo patients, the posterior and anterior semicircular canals are longer than those in people without benign paroxysmal positional vertigo. These morphological changes may contribute to elucidating the aetiopathogenesis and be used as a radiological sign for diagnosis of benign paroxysmal positional vertigo disease.

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Section: Discussionmentioning

confidence: 99%