Asymptomatic syndrome of polycythemic hyperviscosity: effect of partial plasma exchange transfusion

Bada, Henrietta S.; Korones, Sheldon B.; Pourcyrous, Massroor; Wong, S. P.; Wilson, William; Kolni, Harold W; Ford, Diana L.

doi:10.1016/s0022-3476(05)82487-4

Cited by 55 publications

(42 citation statements)

References 16 publications

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“…Restoration of cerebral blood flow velocity abnormalities after PExT has been shown previously. 15 Systemic artery assessments in our study closely mirrored changes in LVO, thereby underlining the importance of maintaining adequate cardiac output in such cases. The relationship of coronary flow and LVO and diastolic function is in agreement with work carried out previously.…”

Section: Impact On Diastolic Functionsupporting

confidence: 69%

Hemodynamic alterations associated with polycythemia and partial exchange transfusion

Sehgal

Francis

2011

J Perinatol

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Polycythemia hyperviscosity syndrome has been associated with multiple systemic effects. There is dearth of data on the effects of polycythemia on cardiac function. This case presents a newborn infant with symptomatic polycythemia in whom detailed myocardial function analysis for systolic and diastolic performance, as well as end-organ perfusion assessment was carried out using transthoracic echocardiography. Hemodynamic information in polycythemic infants before and after partial exchange could improve our understanding of the impact on myocardial performance.

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Section: Impact On Diastolic Functionsupporting

confidence: 69%

Hemodynamic alterations associated with polycythemia and partial exchange transfusion

Sehgal

Francis

2011

J Perinatol

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“…Studies have shown that blood flow and microcirculation improved after partial blood exchange using Doppler ultrasonography and "near infrared" spectroscopy (14,15). However, some studies suggested that partial blood exchange did not contribute to neurological improvement in the neonatal period or in the long-term in symptomatic or asymptomatic infants (4)(5)(6)(7)16,17).…”

Section: Discussionmentioning

confidence: 99%

“…Hyperviscosity which causes slowing of blood flow and disruption of organ perfusion is present in only 47.4% of polycythemic patients (3). In addition, partial blood exchange which is performed to decrease hyperviscosity was not observed to be beneficial for long-term neurodevelopmental status and there are studies showing that partial blood exchange carries a risk in terms of necrotizing enterocolitis (NEC) (4)(5)(6)(7)(8). The aim of this study was to evaluate the effects of clinical course, risk factors and partial blood exchange on short-term mortality and morbidity in polycythemic term and late premature patients.…”

Section: Introductionmentioning

confidence: 99%

Yenidoğan polisitemisinde kısmi kan değişimi

Özalkaya¹,

Topçuoğlu²,

Yıldırım³

et al. 2012

tpa

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“…Most neonatologists perform an exchange transfusion when the peripheral venous haematocrit is above 70% in the absence of symptoms, but this is controversial [1]. The long-term outcome in infants with asymptomatic polycythaemia/hyperviscosity whether treated or untreated remains controversial [9]. For the purpose of an exchange transfusion, normal saline is safe, cheap, easily available and as effective as plasma.…”

Section: Discussionmentioning

confidence: 99%