In this paper, we consider the evolution of spacelike graphic curves defined over a piece of hyperbola H 1 (1), of center at origin and radius 1, in the 2-dimensional Lorentz-Minkowski plane R 2 1 along an anisotropic inverse mean curvature flow with the vanishing Neumann boundary condition, and prove that this flow exists for all the time. Moreover, we can show that, after suitable rescaling, the evolving spacelike graphic curves converge smoothly to a piece of hyperbola of center at origin and prescribed radius, which actually corresponds to a constant function defined over the piece of H 1 (1), as time tends to infinity.