At present, the journal-Management Science(MS) is constantly developing into one of the top international journals in the fields of Management and Operations Research & Management Science. Motivated by a quite good understanding of the development of this journal, this paper carries out this research work on the application of bibliometric methods and techniques to systematically study the standard data of the publications included in the Web of Science from 1999 to 2018. To be specific, the knowledge structure and knowledge characteristic of its development are grasped. The former analyzes the distribution of annual publications, the characteristics of most productive and influential countries, institutions and authors and the latter discussed the research foundation, research topics and research hotspots. Innovatively, the terms of "Product Life Cycle", "Red Sea", "Blue Sea" in the Marketing Management and the time-line map are introduced the analyses on research topics, which is different from other scholars. The results show that both knowledge structure and knowledge characteristic of MS present certain regularities, especially the evolutions of annual publications and researches topics have gone three main stages. To some extent, this paper can help scholars to better understand the journal, and provide some ideas for future scientific research works with higher contributions. In addition, this paper also provides a perspective for researches on journals in combination with bibliometrics and data analysis.