1996
DOI: 10.1080/01621459.1996.10476682
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Asymptotics for the SIMEX Estimator in Nonlinear Measurement Error Models

Abstract: Cook and Stefanski have described a computer-intensive method, the SIMEX method, for approximately consistent estimation in regression problems with additive measurement error. In this article we derive the asymptotic distribution of their estimators and show how to compute estimated standard errors. These standard error estimators can either be used alone or as prepivoting devices in a bootstrap analysis. We also give theoretical justification to some of the phenomena observed by Cook and Stefanski in their s… Show more

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Cited by 150 publications
(102 citation statements)
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“…Second, the estimates are extrapolated backwards to the point where no measurement error existed (extrapolation step). The method can deal with continuous variables measured with random normal error (the original SIMEX procedure; Carroll, Küchenhoff, Lombard, & Stefanski, 1996;Cook & Stefanski, 1994) and with discrete variables measured with misclassification (the MCSIMEX procedure; Küchenhoff, Lederer, & Lesaffre, 2007;Küchenhoff, Mwalili, & Lesaffre, 2006). Similar to matrix correction and errors-in-variables-models, information about the measurement error must be provided.…”
Section: (Misclassification) Simulation Extrapolation ([Mc]simex)mentioning
confidence: 99%
“…Second, the estimates are extrapolated backwards to the point where no measurement error existed (extrapolation step). The method can deal with continuous variables measured with random normal error (the original SIMEX procedure; Carroll, Küchenhoff, Lombard, & Stefanski, 1996;Cook & Stefanski, 1994) and with discrete variables measured with misclassification (the MCSIMEX procedure; Küchenhoff, Lederer, & Lesaffre, 2007;Küchenhoff, Mwalili, & Lesaffre, 2006). Similar to matrix correction and errors-in-variables-models, information about the measurement error must be provided.…”
Section: (Misclassification) Simulation Extrapolation ([Mc]simex)mentioning
confidence: 99%
“…The asymptotic distribution theory for the original SIMEX approach has been developed by Carroll et al (1996), hereafter denoted by CKLS. The idea is to view regression estimation as solving unbiased estimating equations, see e.g.…”
Section: Asymptotic Variance Estimationmentioning
confidence: 99%
“…Thus there is a need for a method which is theoretically justified and can calculate the standard errors in a less computer intensive manner allowing for the uncertainty of the estimated misclassification probabilities. The asymptotic variance estimation has been developed for the original SIMEX by Carroll et al (1996). Here we transfer this strategy to the case of the MC-SIMEX approach.…”
Section: Introductionmentioning
confidence: 99%
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“…It is, however, very computer intensive and it only gives a consistent estimator if the correct extrapolation curve has been used (see Carroll et al, 1996). The quadratic curve may be convenient, but it is rarely the correct curve.…”
Section: Add Random Noise To Thementioning
confidence: 99%