Atherosclerosis precursors in Finnish children and adolescents. I. General description of the cross‐sectional study of 1980, and an account of the children's and families' state of health

Hk, Åkerblom; Viikari, Jorma; Uhari, Matti; Rásänen, Leena; Byckling, T.; Louhivuori, K; Pesonen, Erkki; Suoninen, P.; Pietikäinen, M; Pl, Lähde

doi:10.1111/j.1651-2227.1985.tb10082.x

Cited by 195 publications

(99 citation statements)

References 27 publications

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“…In 1980, children and adolescents age 3, 6, 9, 12, 15, or 18 years (n ϭ 4,320) were invited to participate in the first cross-sectional assessment. Of those invited, 3,596 (83%) participated (Table 1) (20). The study was carried out in 5 Finnish university cities (Helsinki, Kuopio, Oulu, Tampere, and Turku) and their surrounding rural municipalities.…”

Section: Methodsmentioning

confidence: 99%

Incidence of nonspecific and radiating low back pain: followup of 24–39‐year‐old adults of the Young Finns Study

Shiri

Solovieva

Husgafvel‐Pursiainen

et al. 2010

Arthritis Care & Research

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Objective. The full panorama of the types and severity of low back pain during the life course is poorly known. We studied the incidence and severity of nonspecific and radiating low back pain based on a recent followup on a representative sample of the Finnish general population. Methods. As part of the ongoing Young Finns Study, participants ages 24 -39 years who were free from low back pain at baseline in 2001 were included (n ‫؍‬ 1,224). We estimated the incidence of nonspecific and radiating low back pain in 2007.Results. The incidence of moderate (8 -30 days duration in the past 12 months) nonspecific low back pain was 13.2%, and that of radiating low back pain was 8.6%. The rates did not differ between men and women. The incidence of major (>30 days in the past 12 months) nonspecific low back pain was 7.8%, and that of radiating low back pain was 3.4%. The incidence of major nonspecific low back pain was higher in women than in men (P ‫؍‬ 0.02). Moderate as well as major nonspecific low back pain declined with age, whereas major radiating low back pain increased with age. Conclusion. Our findings indicate that low back pain is a common condition in adults already in their 30s. It becomes more severe around the age of 40 years, showing different development of nonspecific and radiating low back pain. We recommend monitoring low back health in health surveillance, starting early and differentiating between nonspecific and radiating pain.

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Section: Methodsmentioning

confidence: 99%

Incidence of nonspecific and radiating low back pain: followup of 24–39‐year‐old adults of the Young Finns Study

Shiri

Solovieva

Husgafvel‐Pursiainen

et al. 2010

Arthritis Care & Research

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“…The subjects were derived from a population-based, prospective cohort study called The Cardiovascular Risk in Young Finns Study (Akerblom et al 1985). The cohort originally consisted of 3596 randomly selected healthy individuals from six age cohorts (3,6,9,12,15 and 18 years) at baseline in 1980.…”

Section: Subjectsmentioning

confidence: 99%

Temperament, character and serotonin activity in the human brain: a positron emission tomography study based on a general population cohort

et al. 2012

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Tuominen, L.; Salo, J.; Hirvonen, J.; Någren, K.; Laine, P.; Melartin, T.; Isometsä, E.; Viikari, J.; Cloninger, C. R.; Raitakari, O.; Hietala, J.; and Keltikangas-Järvinen, L., ,"Temperament, character and serotonin activity in the human brain: A positron emission tomography study based on a general population cohort." Psychological Medicine. 43,4. 881-894. (2012 Background. The psychobiological model of personality by Cloninger and colleagues originally hypothesized that interindividual variability in the temperament dimension ' harm avoidance ' (HA) is explained by differences in the activity of the brain serotonin system. We assessed brain serotonin transporter (5-HTT) density in vivo with positron emission tomography (PET) in healthy individuals with high or low HA scores using an ' oversampling ' study design.Method. Subjects consistently in either upper or lower quartiles for the HA trait were selected from a populationbased cohort in Finland (n=2075) with pre-existing Temperament and Character Inventory (TCI) scores. A total of 22 subjects free of psychiatric and somatic disorders were included in the matched high-and low-HA groups. The main outcome measure was regional 5-HTT binding potential (BP ND ) in high-and low-HA groups estimated with PET and [ 11 C]N,N-dimethyl-2-(2-amino-4-methylphenylthio)benzylamine ([ 11 C]MADAM). In secondary analyses, 5-HTT BP ND was correlated with other TCI dimensions.Results. 5-HTT BP ND did not differ between high-and low-HA groups in the midbrain or any other brain region. This result remained the same even after adjusting for other relevant TCI dimensions. Higher 5-HTT BP ND in the raphe nucleus predicted higher scores in ' self-directedness '.Conclusions. This study does not support an association between the temperament dimension HA and serotonin transporter density in healthy subjects. However, we found a link between high serotonin transporter density and high ' self-directedness ' (ability to adapt and control one's behaviour to fit situations in accord with chosen goals and values). We suggest that biological factors are more important in explaining variability in character than previously thought.

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“…The Cardiovascular Risk in Young Finns Study (YFS; Åkerblom, Viikari, Uhari, Räsänen, Byckling, Louhivuori et al, 1985;Raitakari, Juonala, & Rönnemaa, 2008) is an ongoing follow-up study undertaken on six cohorts born in 1962, 1965, 1968, 1971, 1974and 1977. In 1980 were randomly selected from the Finnish national register of the study areas: Helsinki, Kuopio, Oulu, Tampere, and Turku and their surrounding communities.…”

Section: Participantsmentioning

confidence: 99%

Convergent Validity of a Physical Activity Questionnaire against Objectively Measured Physical Activity in Adults: The Cardiovascular Risk in Young Finns Study

Hirvensalo¹,

Magnussen²,

Yang³

et al. 2017

APE

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Background: Traditionally, a self-reported questionnaire has been a cost-effective method of gathering information about physical activity (PA). An objective measurement, such as the use of a pedometer, can be used to validate the findings of a PA questionnaire in a large population. Objective: The study objective was to determine the convergent validity of a PA questionnaire against objectively measured PA in adults obtained with the use of a pedometer. Methods: Data from the Cardiovascular Risk in Young Finns Study (YFS) were collected from 1853 participants aged 30 -45 years. The participants completed a self-reported questionnaire that included items on leisure time, commuting and habitual PA. PA was expressed as leisure-time physical activity index (PAI) and metabolic equivalent hours/week (METh/wk). The participants wore a pedometer for seven consecutive days and used it to record their total daily and aerobic steps. Results: There was a low to moderate association between the self-reported questionnaire and pedometer measurements regarding both total steps and aerobic steps taken during leisure time and commuting PA. An association was not observed between peHow to cite this paper: Hirvensalo, M., Magnussen, C. G., Yang, X. L., Telama, R., Heinonen, I., Hutri-Kähönen, N., Salin, K., Viikari, J., Raitakari, O. T., & Tammelin

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Atherosclerosis precursors in Finnish children and adolescents. I. General description of the cross‐sectional study of 1980, and an account of the children's and families' state of health

Cited by 195 publications

References 27 publications

Incidence of nonspecific and radiating low back pain: followup of 24–39‐year‐old adults of the Young Finns Study

Incidence of nonspecific and radiating low back pain: followup of 24–39‐year‐old adults of the Young Finns Study

Temperament, character and serotonin activity in the human brain: a positron emission tomography study based on a general population cohort

Convergent Validity of a Physical Activity Questionnaire against Objectively Measured Physical Activity in Adults: The Cardiovascular Risk in Young Finns Study

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