Atherosclerotic renal artery stenosis

Abstract

Although the atherosclerotic lesions of the renal arteries tend to progress over time, the anatomical lesion progression is not always associated with changes in BP. Furthermore, a poor correlation was noted between the degree of anatomic stenosis and glomerular filtration rate. The high cardiovascular risk warrants aggressive pharmacological treatment to prevent progression of the generalized vascular disorder. Ongoing trials will show whether PTRA revascularization has added, long-term effects on BP, renal function, and cardiovascular prognosis. With or without PTRA revascularization, medical therapy using antihypertensive agents, statins, and aspirin is necessary in almost all cases.

Endocrine and Hypertensive Disorders of Potassium Regulation: Primary Aldosteronism

“…The latter, in particular, also lead to potassium homeostasis disorders. We briefly review the screening for these conditions in the evaluation of the patient with resistant hypertension; excellent recent reviews of the evaluation and management of renovascular hypertension are available to the interested reader 9–11 , and discussion of genetic disorders leading to altered renal sodium and potassium transport and thereby causing resistant hypertension are available in this issue of Seminars in Nephrology .…”