Atherosclerotic Renovascular Hypertension : Lessons from Recent Clinical Studies

Abstract

Atherosclerotic renovascular hypertension is a form of secondary hypertension due to renal artery stenosis. After the introduction of medical therapy such as with statins and angiotensin blocking agents, it has been considered a very slowly progressive disease. In the 1990s, surgical methods were compared to radiological intervention and showed no additional benefits. Recent clinical data also demonstrate that in cases of relatively stable atherosclerotic renovascular disease, medical therapy is as effective as other interventions with regard to patient outcomes. In this paper the recent clinical outcomes are reviewed.

Research of multiarterial atherosclerotic disease in hypertensive patients with renal artery stenosis

“…3,4 Tal achado também pode ser observado pelo fato de que 2/3 dos pacientes já apresentava critérios para síndrome metabólica, o que reflete a presença de múltiplos fatores de risco metabólico para doença cardiovascular. Curiosamente, ao contrário da relação já comprovada na literatura entre Diabetes Mellitus tipo 2 e estenose de artéria renal, 5,6,8,24 nossos pacientes eram em sua maioria não-diabéticos.…”