Background
Ascending aortic dimensions are slightly larger in young competitive athletes compared to sedentary controls, but rarely greater than 40 mm. Whether this finding translates to aortic enlargement in older, former athletes is unknown.
Methods and Results
This cross-sectional study involved a sample of 206 former National Football League (NFL) athletes compared with 759 male subjects from the Dallas Heart Study-2 (DHS) (mean age 57.1 and 53.6 years respectively, p < 0.0001; body surface area of 2.4 and 2.1 m2 respectively, p < 0.0001). Mid-ascending aortic dimensions were obtained from computed tomographic scans performed as part of a NFL screening protocol or as part of the DHS. Compared to a population based control group, former NFL athletes had significantly larger ascending aortic diameters (38±5 vs. 34±4 mm; p<0.0001). A significantly higher proportion of former NFL athletes had an aorta of greater than 40 mm (29.6% versus 8.6%, p<0.0001). After adjusting for age, race, body surface area, systolic blood pressure, history of hypertension, current smoking, diabetes, and lipid profile the former NFL athletes still had significantly larger ascending aortas (p<0.0001). Former NFL athletes were twice as likely to have an aorta greater than 40 mm after adjusting for the same parameters.
Conclusions
Ascending aortic dimensions were significantly larger in a sample of former NFL athletes after adjusting for their size, age, race and cardiac risk factors. Whether this translates to an increased risk is unknown and requires further evaluation.