The complex interactions between soil and additives such as lignin, glass powder, and rubber tires were investigated using principles of material and soil mechanics. Previous research has mainly focused on individual additives in clay soils. In contrast, this study investigates soil improvement with two different types of waste materials simultaneously. The improvement of soil properties by hybrid waste materials was evaluated using several laboratory tests, including the standard Proctor test, the unconfined compressive strength test, the California Bearing Ratio (CBR) test, and cyclic triaxial tests. The aim of this research is to identify key parameters for the design and construction of road pavements and to demonstrate that improving the subgrade with hybrid waste materials contributes significantly to the sustainability of road construction. The mechanical and physical properties were evaluated in detail to determine the optimal mixtures. The results show that the most effective mixture for the combination of waste glass powder and rubber tires contains 20% glass powder and 3% rubber tires, based on the dry weight of the soil. For the combination of waste glass powder and lignin, the optimum mixture consists of 15% glass powder and 15% lignin, based on the dry weight of the soil. These results provide valuable insights into the sustainable use of waste materials for soil stabilization in road construction projects.