<p><strong>Objective: </strong>Oral candidiasis is the most common fungal infection of the oral cavity, and <em>Candida albicans</em> is the most frequently isolated species. <strong>Material and Methods:</strong> In this study, the potential antifungal effect of extracts from <em>Gossypium hirsutum </em>L., <em>Arctium lappa</em>,<em> Equisetum </em>sp<em>.</em>, <em>Cecropia pachystachya </em>Trécul and <em>Pogostemon heyneanus</em> plants were evaluated on non-adhered cells of <em>C. albicans</em>, and the effect of oral antiseptics A (cetylpyridinium chloride 0.500 mg), B (chlorhexidine gluconate 0.12%), C (hydrogen peroxide 1.5%) and D (thymol, eucalyptol, menthol and methyl salicylate) were evaluated on non-adhered cells and biofilms of C. albicans, using turbidimetry and minimal inhibitory concentration (MIC) of the extracts and the maximal inhibitory dilution (MID) of the antiseptics. <strong>Results:</strong> The most promising results on non-adhered cells were obtained with <em>Cecropia pachystachya</em>Trécul extracts, with MIC values between 7.81 and 3.91 µg/mL. Antiseptics A and B showed the lowest MID values, between 0.20 and 0.10% (Kruskal-Wallis, p<0.0001). Regarding biofilm inhibition, the MID values found were similar for the tested antiseptics, varying from 50% to 0.20% (Kruskal-Wallis, p=0.6915). <strong>Conclusion:</strong> These results show that some plant extracts has potential use in the prevention and treatment of oral candidiasis. </p>