Atividade antioxidante da Própolis de Abelhas Jataí / Antioxidant activity Of Propolis of Jataí Bees

Freitas, Carlos Filipe; Bilibio, Denise; Santos, Lára Franco dos; Botton, Nadálin Yandra; Santos, Luciana Ruschel dos

doi:10.34188/bjaerv4n1-080

Cited by 3 publications

(3 citation statements)

References 15 publications

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“…Phenolic compounds, especially flavonoids, have adequate structure for radical scavenging, which makes them more effective antioxidants than vitamins C and E [71]. The strong antioxidant activity of plant extracts and apiculture products has been associated with their high contents especially of flavonoids [72]. Most flavonoids have biological activities, such as the antioxidant, anti-inflammatory and antibacterial ones, which are of great importance to the food, cosmetic and pharmaceutical sectors [73] and have aroused interest in the discovery of new natural compounds capable of minimizing oxidative damage to cells [48].…”

Section: Discussionmentioning

confidence: 99%

Characterization, Biocompatibility and Antioxidant Activity of Hydrogels Containing Propolis Extract as an Alternative Treatment in Wound Healing

Ferreira,

Modesto,

Souza

et al. 2024

Pharmaceuticals

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Hydrogels consist of a network of highly porous polymeric chains with the potential for use as a wound dressing. Propolis is a natural product with several biological properties including anti-inflammatory, antibacterial and antioxidant activities. This study was aimed at synthesizing and characterizing a polyacrylamide/methylcellulose hydrogel containing propolis as an active ingredient, to serve as a wound dressing alternative, for the treatment of skin lesions. The hydrogels were prepared using free radical polymerization, and were characterized using scanning electron microscopy, infrared spectroscopy, thermogravimetry, differential scanning calorimetry, swelling capacity, mechanical and rheological properties, UV-Vis spectroscopy, antioxidant activity by the DPPH, ABTS and FRAP assays and biocompatibility determined in Vero cells and J774 macrophages by the MTT assay. Hydrogels showed a porous and foliaceous structure with a well-defined network, a good ability to absorb water and aqueous solutions simulating body fluids as well as desirable mechanical properties and pseudoplastic behavior. In hydrogels containing 1.0 and 2.5% propolis, the contents of total polyphenols were 24.74 ± 1.71 mg GAE/g and 32.10 ± 1.01 mg GAE/g and those of total flavonoids 8.01 ± 0.99 mg QE/g and 13.81 ± 0.71 mg QE/g, respectively, in addition to good antioxidant activity determined with all three methods used. Therefore, hydrogels containing propolis extract, may serve as a promising alternative wound dressing for the treatment of skin lesions, due to their anti-oxidant properties, low cost and availability.

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Section: Discussionmentioning

confidence: 99%

Characterization, Biocompatibility and Antioxidant Activity of Hydrogels Containing Propolis Extract as an Alternative Treatment in Wound Healing

Ferreira,

Modesto,

Souza

et al. 2024

Pharmaceuticals

View full text Add to dashboard Cite

show abstract

Section: Antioxidant Activitymentioning

confidence: 99%

“…The food industry uses synthetic antioxidants for food preservation, but their use raises concerns about safe doses and toxicity; therefore, the interest of researchers in the search for natural substitutes has increased [74]. Secondary metabolites, including flavonoids, are the compounds mainly responsible for the antiradical power of plant extracts and bee products [74]. Antioxidants are compounds that, in small quantity compared to the oxidizable substrate, delay the start or prevent the onset or propagation of the oxidation reaction chain, in addition to inhibiting lipid peroxidation as well as the oxidation of other macromolecules and DNA [52].…”

Section: Antioxidant Activitymentioning

confidence: 99%

Preliminary Study on the Chemical and Biological Properties of Propolis Extract from Stingless Bees from the Northern Region of Brazil

Ferreira,

Souza,

Pereira

et al. 2024

Processes

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Natural products are historically regarded as the main sources of bioactive compounds to fight the most diverse diseases; among them, propolis deserves to be highlighted due to several biological activities, such as antioxidant, anti-inflammatory, healing, antibacterial and antileishmanial activity. In this study, the antioxidant and antipromastigote activities and the cytotoxicity of propolis of the Scaptotrigona aff. postica stingless bee were evaluated. Propolis extract was analyzed by infrared spectroscopy, thermogravimetry and spectrophotometry for total polyphenols and flavonoid contents. Antioxidant activity was assessed spectrophotometrically by the DPPH, ABTS and FRAP methods, while antipromastigote activity and cytotoxicity were assessed by the MTT assay. The infrared spectra showed the characteristic bands of both phenols and alcohols. The thermogravimetry study revealed two events and thermal stability around 370 °C, while differential scanning calorimetry showed two endothermic events and an exothermic event. Total polyphenol and flavonoid contents were 21.29 ± 0.003 mg/g and 8.17 ± 0.00 mg/g, respectively, and the antioxidant activities identified by the DPPH, ABTS and FRAP methods were 910.09 ± 0.0264 µM Trolox (IC50 18.9 ± 0.01 µg/mL), 859.97 ± 0.0854 µM Trolox (IC50 692 ± 0.01 µg/mL) and 1613.67 ± 0.2610 µM Trolox (IC50 80 ± 0.1 µg/mL), respectively. The satisfactory antioxidant activity of propolis can be related to the high content of phenolic compounds, which adds value to this product and can contribute to the development of meliponiculture in the Brazilian state of Pará. The propolis extract caused a toxic effect on promastigote forms of Leishmania amazonensis at all concentrations tested, with an IC50 value of 1.50 µg/mL and a statistically significant difference compared to the negative control (p < 0.001). These results show that the propolis extract from S. postica bees may be a promising alternative for treatment against promastigote forms of L. amazonensis.

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Metabolomic Comparison between Honey, Propolis, and Pollen from Brazilian Stingless Bees

Schuerts,

Leite,

Peiter

et al. 2024

ACS Food Sci. Technol.

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Atividade antioxidante da Própolis de Abelhas Jataí / Antioxidant activity Of Propolis of Jataí Bees

Cited by 3 publications

References 15 publications

Characterization, Biocompatibility and Antioxidant Activity of Hydrogels Containing Propolis Extract as an Alternative Treatment in Wound Healing

Characterization, Biocompatibility and Antioxidant Activity of Hydrogels Containing Propolis Extract as an Alternative Treatment in Wound Healing

Preliminary Study on the Chemical and Biological Properties of Propolis Extract from Stingless Bees from the Northern Region of Brazil

Metabolomic Comparison between Honey, Propolis, and Pollen from Brazilian Stingless Bees

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