1995
DOI: 10.1017/s0022215100131883
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Atlanto-axial subluxation (Grisel's syndrome) following otolaryngological diseases and procedures

Abstract: Grisel's syndrome is a rare condition of uncertain aetiology characterized by atlanto-axial subluxation following an infection in the head and neck region. The condition most frequently affects children and characteristically presents in the post-operative period with cervical pain and torticollis. We describe three cases and discuss the aetiology and pathogenesis. A high index of suspicion may lead to early diagnosis in its natural history thereby preventing potentially serious complications.

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Cited by 46 publications
(29 citation statements)
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“…Sipila et al [5] 2 T Robinson and De Boer [6] 1 Pharyngoplasty Hopla et al [7] 2 First: otitis media, second: choanal atresia Boiten et al [8] 2 U R T I Sangermani et al [9] 1 T A Robertson et al [10] 1 R P A Antoniuk [11] 1 T Mathern and Batzdorf [12] 2 U R T I Eadie et al [13] 2 Pharyngoplasty Singer [14] 2 T A Litman and Perkins [15] 1 Tympanomastoidectomy& trisomy21 Prado et al [16] 1 R P A Samuel et al [17] 3 T A Baker et al [18] 2 T A Nucci et al [19] 1 Instilling eye drops& Downs syndrome Welinder et al [20] 1 R P A Onerci et al [21] 1 T A Kelly et al [22] 1 Bilateral otoplasty *Subach et al [23] 20 7 URTI, 4 TA, 4 trauma, 5 idiopathic Bedi et al [24] 1 T A Dasen [25] 1 T Brisson [26] 1 Central line placement Cunnington and Mongia [27] 1 Pharyngeal abscess Al-Jishi and Sreekantaswamy [28] 1 Primary dystonia Meek et al [29] 1 Pharyngoplasty and grommets in cleft palate case Kraft and Tschopp [30] 3 A Holcomb et al [31] 4 URTI, TA *Martinez-Lage et al [32] 4 3 trauma, 1 OM Guleryuz et al [33] 1 U R T I Gourin et al [34] 1 R P A Okada et al [35] 1 Mumps Mezue et al [36] 13 URTI Kasten et al [37] 1 U R T I Tschopp [38] 3 Monopolar electrocautery and A Ugur et al [39] 2 U R T I Lehtinen et al [40] 1 U R T I Yu et al [41] 1 T A Fernandez-Cornejo et al [42] 4 U R T I Hirth and Welkoborsky …”
Section: Referencementioning
confidence: 99%
“…Sipila et al [5] 2 T Robinson and De Boer [6] 1 Pharyngoplasty Hopla et al [7] 2 First: otitis media, second: choanal atresia Boiten et al [8] 2 U R T I Sangermani et al [9] 1 T A Robertson et al [10] 1 R P A Antoniuk [11] 1 T Mathern and Batzdorf [12] 2 U R T I Eadie et al [13] 2 Pharyngoplasty Singer [14] 2 T A Litman and Perkins [15] 1 Tympanomastoidectomy& trisomy21 Prado et al [16] 1 R P A Samuel et al [17] 3 T A Baker et al [18] 2 T A Nucci et al [19] 1 Instilling eye drops& Downs syndrome Welinder et al [20] 1 R P A Onerci et al [21] 1 T A Kelly et al [22] 1 Bilateral otoplasty *Subach et al [23] 20 7 URTI, 4 TA, 4 trauma, 5 idiopathic Bedi et al [24] 1 T A Dasen [25] 1 T Brisson [26] 1 Central line placement Cunnington and Mongia [27] 1 Pharyngeal abscess Al-Jishi and Sreekantaswamy [28] 1 Primary dystonia Meek et al [29] 1 Pharyngoplasty and grommets in cleft palate case Kraft and Tschopp [30] 3 A Holcomb et al [31] 4 URTI, TA *Martinez-Lage et al [32] 4 3 trauma, 1 OM Guleryuz et al [33] 1 U R T I Gourin et al [34] 1 R P A Okada et al [35] 1 Mumps Mezue et al [36] 13 URTI Kasten et al [37] 1 U R T I Tschopp [38] 3 Monopolar electrocautery and A Ugur et al [39] 2 U R T I Lehtinen et al [40] 1 U R T I Yu et al [41] 1 T A Fernandez-Cornejo et al [42] 4 U R T I Hirth and Welkoborsky …”
Section: Referencementioning
confidence: 99%
“…The etiopathogenesis of this clinical entity is not clear yet [6,7]. C-reactive protein (CRP) was 24.98 mg/dl, and the white blood cell count (WBC) was 7.100 U/ml.…”
Section: Discussionmentioning
confidence: 99%
“…It is generally accepted that the process is initiated by an infection in the upper cervical region which creates an inflammatory milieu. Grisel postulated that AAS was caused by muscle spasm; now muscle spasm is thought to be a reaction to adjacent inflammation and the role of this muscle spasm is limited to maintenance of the subluxed position but is not causative [1,2]. Hyperemia of the blood supply of bone has been shown to cause resorption.…”
Section: Discussionmentioning
confidence: 99%