Atlas of axial spondyloarthritis in Spain 2017: Study design and population

Garrido‐Cumbrera, Marco; Navarro-Compán, Victoria; Zarco, Pedro; Collantes-Estévez, Eduardo; Ruiz, David Gálvez; Braçe, Olta; García, Jorge Chacón; Mur, C.; Ferrer, Angels Costa; Hidalgo, Álvaro; Ramos, Pedro Plazuelo; Masmitjá, Jordi Gratacós

doi:10.1016/j.reumae.2018.09.010

Cited by 7 publications

(11 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…EMAS was an observational, cross-sectional survey of unselected patients self-reporting as axSpA from Austria, Belgium, France, Germany, Italy, the Netherlands, Norway, Russia, Slovenia, Spain, Sweden, Switzerland and the UK. The survey questionnaire was adapted from the Spanish Atlas of Axial Spondyloarthritis 2017 [ 17 ], a patient survey held from January to March 2016 promoted by Health and Territory Research and CEADE, with the support of the Max Weber Institute and Novartis Farmacéutica Spain. The data from the Atlas of Axial Spondyloarthritis in Spain 2017 [ 18 ] was retrospectively added to the EMAS database.…”

Section: Methodsmentioning

confidence: 99%

“…This firm ensures that patients are fully vetted through their contacted healthcare professionals around the world, who refer their patients to patient market research. The database from the Atlas of Axial Spondyloarthritis in Spain 2017 [ 17 ] was retrospectively added to the EMAS database. In Austria, France, Spain, Norway, Slovenia, Sweden, the Netherlands, Italy, Russia and Switzerland, axSpA-specific patient organizations also supported recruitment by distributing the survey to their associated members (Fig.…”

Section: Methodsmentioning

confidence: 99%

“…The survey questionnaire was adapted from the Spanish Atlas of Axial Spondyloarthritis 2017 [17], a patient survey held from January to March 2016 promoted by Health and Territory Research and CEADE, with the support of the Max Weber Institute and Novartis Farmacéutica Spain. The data from the Atlas of Axial Spondyloarthritis in Spain 2017 [18] was retrospectively added to the EMAS database.…”

Section: Design and Survey Developmentmentioning

confidence: 99%

See 2 more Smart Citations

Gender differences in patient journey to diagnosis and disease outcomes: results from the European Map of Axial Spondyloarthritis (EMAS)

et al. 2021

Self Cite

View full text Add to dashboard Cite

Introduction/objectives To evaluate the journey to diagnosis, disease characteristics and burden of disease in male and female patients with axial spondyloarthritis (axSpA) across Europe. Method Data from 2846 unselected patients participating in the European Map of Axial Spondyloarthritis (EMAS) study through an online survey (2017–2018) across 13 countries were analysed. Sociodemographic characteristics, lifestyle, diagnosis, disease characteristics and patient-reported outcomes (PROs) [disease activity –BASDAI (0–10), spinal stiffness (3–12), functional limitations (0–54) and psychological distress (GHQ-12)] were compared between males and females using chi-square (for categorical variables) and student t (for continuous variables) tests. Results In total, 1100 (38.7%) males and 1746 (61.3%) females participated in the EMAS. Compared with males, females reported considerable longer diagnostic delay (6.1 ± 7.4 vs 8.2 ± 8.9 years; p < 0.001), higher number of visits to physiotherapists (34.5% vs 49.5%; p < 0.001) and to osteopaths (13.3% vs 24.4%; p < 0.001) before being diagnosed and lower frequency of HLA-B27 carriership (80.2% vs 66.7%; p < 0.001). In addition, females reported higher degree of disease activity in all BASDAI aspects and greater psychological distress through GHQ-12 (4.4 ± 4.2 vs 5.3 ± 4.1; p < 0.001), as well as a greater use of alternative therapies. Conclusion The patient journey to diagnosis of axSpA is much longer and arduous in females, which may be related to physician bias and lower frequency of HLA-B27 carriership. Regarding PROs, females experience higher disease activity and poorer psychological health compared with males. These results reflect specific unmet needs in females with axSpA needing particular attention. Key Points• Healthcare professionals’ perception of axSpA as a predominantly male disease may introduce some bias during the diagnosis and management of the disease. However, evidence about male-female differences in axSpA is scarce.• EMAS results highlight how female axSpA patients report longer diagnostic delay and higher burden of the disease in a large sample of 2846 participants of 13 European countries.• Results reflect unmet needs of European female patients. Healthcare professionals should pay close attention in order to accurately diagnose and efficiently manage axSpA cases while further research should be developed on the cause of reported gender differences.

show abstract

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Design and Survey Developmentmentioning

confidence: 99%

See 1 more Smart Citation

Gender differences in patient journey to diagnosis and disease outcomes: results from the European Map of Axial Spondyloarthritis (EMAS)

et al. 2021

Self Cite

View full text Add to dashboard Cite

show abstract

“…The EMAS project continues expanding, being currently carried out in additional countries in Africa, America, Asia, and Europe under the new brand International Map of Axial Spondyloarthritis (IMAS). More information about the Atlas 14 and EMAS 15 can be found in their seminal studies.…”

Section: Methodsmentioning

confidence: 99%

“…The Atlas of Axial Spondyloarthritis in Spain is a cross‐sectional study gathering data through an online survey of 680 unselected patients with self‐reported axSpA diagnosis 14 . This Spanish survey was adapted into the EMAS survey, which recruited an additional 2166 axSpA patients from 12 different European countries other than Spain: Austria, Belgium, France, Germany, Italy, the Netherlands, Norway, Russia, Slovenia, Sweden, Switzerland, the United Kingdom.…”

Section: Methodsmentioning

confidence: 99%

A Benchmarking Study Evaluating Axial Spondyloarthritis Burden in Spain and Other European Countries. Results from the Spanish Atlas and the European Map of Axial Spondyloarthritis (EMAS) Studies

Garrido‐Cumbrera

Gratacós²,

Collantes-Estévez

et al. 2021

Int J of Rheum Dis

View full text Add to dashboard Cite

Aim To compare the burden of disease in Spanish patients with axial spondyloarthritis (axSpA) vs other European countries (OEC). Methods Data from 2846 unselected patients from the European Map of Axial Spondyloarthritis (EMAS) and the Atlas of Axial Spondyloarthritis in Spain (Atlas) were collected through online surveys. Comparative analysis was carried out between Spanish patients (2016) and patients from 12 OEC ( 2017‐2018). Socio‐demographic characteristics, life habits, and patient‐reported outcomes (Bath Ankylosing Spondylitis Disease Activity Index 0‐10, spinal stiffness 3‐12, functional limitation 0‐54, the 12‐Item General Health Questionnaire [GHQ‐12] for psychological distress 0‐12) were compared. Chi‐square and Mann‐Whitney tests were used for qualitative and quantitative variables respectively. Results 680 (23.9%) Spanish axSpA patients were compared to 2166 axSpA patients (76.1%) from OEC. Compared to Spain, the OEC group had a higher percentage of females (64.1% vs 52.5%; P < .001) and university‐educated participants (51.7% vs 36.9%; P < .001). Spanish patients showed a greater diagnostic delay (8.5 ± 7.7 vs 7.2 ± 8.6 years; P < .001), visits to orthopedic specialists before diagnosis (56.9% vs 25.3%; P < .001), human leukocyte antigen‐B27 carriership (77.1% vs 70.1%; P = .003), disease activity (5.7 ± 2.0 vs 5.4 ± 2.0; P = .024), and higher unemployment rates (21.7% vs 9.2%; P < .001). Despite lower rates of diagnosed anxiety and depression, Spanish patients were at higher risk of psychological distress according to the GHQ‐12 (5.7 ± 4.5 vs 4.8 ± 4.0; P < .001). Conclusion Compared to European axSpA patients, Spanish patients experience a longer diagnostic delay and greater psychological distress. Being wrongly referred to orthopedic specialists and facing a more precarious labor scenario appear as possible causal factors, highlighting the need to increase the number of rheumatologists, the training of healthcare professionals, and improving axSpA patients' working conditions.

show abstract

An Update on Diagnosis and Classification of Axial Spondyloarthritis

Navarro-Compán

2019

Curr Rheumatol Rep

View full text Add to dashboard Cite

Atlas of axial spondyloarthritis in Spain 2017: Study design and population

Cited by 7 publications

References 22 publications

Gender differences in patient journey to diagnosis and disease outcomes: results from the European Map of Axial Spondyloarthritis (EMAS)

Gender differences in patient journey to diagnosis and disease outcomes: results from the European Map of Axial Spondyloarthritis (EMAS)

A Benchmarking Study Evaluating Axial Spondyloarthritis Burden in Spain and Other European Countries. Results from the Spanish Atlas and the European Map of Axial Spondyloarthritis (EMAS) Studies

An Update on Diagnosis and Classification of Axial Spondyloarthritis

Contact Info

Product

Resources

About