This study investigated the AQI (air quality index) and atmospheric pollutants including PM 2.5 , PM 10 , CO, SO 2 , NO 2 and O 3 in Chongqing, Luzhou and Chengdu from 2017 to 2019. In addition, the impacts of the COVID-19 event on the air quality in the three cities in 2020 were compared and discussed. For the combined AQIs for the three cities, in spring, the daily AQIs ranged between 25 and 182 and averaged 72.1. In summer, the daily AQIs ranged between 24 and 206 and averaged 77.5. In autumn, the daily AQIs ranged between 22 and 170 and averaged 61.1, and in winter, the daily AQIs ranged between 28 and 375 and averaged 99.6. The distributions of the six AQI classes in spring were 3%, 94%, 3%, 0%, 0%, and 0%; in summer, they were 11%, 74%, 15%, 0%, 0% and 0%; in autumn, they were 29%, 70%, 1%, 0%, 0%, and 0%, and in winter, they were 1%, 52%, 44%, 3%, 0%, and 0%, respectively. The average AQIs, in order, were Chengdu (85.4) > Chongqing (73.8) > Luzhou (73.2). Both the highest AQIs and PM 2.5 (as the major indicatory air pollutant) occurred mainly in the low temperature season (January, December, and February), while O 3 was the main air pollutant in June and August when the weather was hot. In February 2020, during the epidemic prevention and control actions taken in response to COVID-19 for the three cities, the combined AQIs for the top five days with the highest