A simulation tool has been developed to model the wind fields, turbulence fields, and the dispersion of Chemical, Biological, Radiological and Nuclear (CBRN) substances in urban areas on the building to city blocks scale. A Computational Fluid Dynamics (CFD) approach has been taken that naturally accounts for critical flow and dispersion processes in urban areas, such as channeling, lofting, vertical mixing and turbulence, by solving the steady-state, Reynolds-Averaged Navier-Stokes (RANS) equations. Rapid generation of high quality cityscape volume meshes is attained by a unique voxel-based model generator that directly interfaces with common Geographic Information Systems (GIS) file formats. The flow and turbulence fields are obtained by solving the steady-state RANS equations using a collocated, pressure-based approach formulated for unstructured and polyhedral mesh elements. Turbulence modeling is based upon the Renormalization Group variant of the k-ε model (k-ε RNG). Neutrally buoyant simulations are made by prescribing velocity boundary condition profiles found by a power-law relationship, while turbulence quantities boundary conditions are defined by a prescribed mixing length in conjunction with the assumption of turbulence equilibrium. Dispersion fields are computed by solving an unsteady transport equation of a dilute gas, formulated in a Eulerian framework, using the velocity and turbulence fields found from the steady-state RANS solution. In this paper the model is explained and detailed comparisons of predicted to experimentally obtained velocity, turbulence and dispersion fields are made to neutrally stable wind tunnel and hydraulic flume experiments.Key words: Urban area transport and dispersion, computational fluid dynamics Nomenclature C tracer gas concentration k turbulence kinetic energy l turbulence length scale P turbulence kinetic energy production rate Q tracer mass source rate ε turbulence kinetic energy dissipation rate µ laminar viscosity coefficient