Atomic Layer Deposition of TiO<sub>2</sub> on Si Window Enables <i>In Situ</i> ATR-SEIRAS Measurements in Strong Alkaline Electrolytes

Zhang, Wei-Yi; Ma, Xian-Yin; Jiang, Tian-Wen; Xu, Xindi; Ni, Baoxin; Chen, Bin; Wang, Yunyu; Jiang, Kun; Cai, Wen-Bin

doi:10.1021/acs.analchem.4c01985

Anal. Chem.

2024

DOI: 10.1021/acs.analchem.4c01985

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Atomic Layer Deposition of TiO₂ on Si Window Enables In Situ ATR-SEIRAS Measurements in Strong Alkaline Electrolytes

Wei-Yi Zhang,

Xian-Yin Ma,

Tian-Wen Jiang

et al.

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Cited by 2 publications

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Attenuated total reflection infrared spectroscopy for studying electrochemical cycling of hydrogen, carbon, and nitrogen-containing molecules

Liu,

Zhao,

Liu

et al. 2024

Journal of Energy Chemistry

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Attenuated total reflection infrared spectroscopy for studying electrochemical cycling of hydrogen, carbon, and nitrogen-containing molecules

Liu,

Zhao,

Liu

et al. 2024

Journal of Energy Chemistry

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Immunosensing of Cardiac Troponin I (cTnI) Using a Two-Electrode Electrochemiluminescence Platform with Near Persisting Luminescence Generated on a Ru(bpy)₃²⁺-Tripropylamine System

Kala,

Rajeevan,

Madanan

et al. 2024

ACS Appl. Bio Mater.

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An economical, rapid, and ultrasensitive detection of biomolecules in clinical settings is very crucial, particularly for the early detection of Cardiac Troponin I (cTnI), which is the gold standard biomarker for Acute Myocardial Infarction (AMI). Electrochemiluminescence (ECL) has risen in prominence as an important technique for in vitro diagnosis and detection by virtue of its high sensitivity reaching a femtomolar level. This study introduces an economically feasible nanoplatform for ECL immunosensing, consisting of a gold nanoparticle (AuNP) with Ru(bpy) 3 2+ and tripropylamine (TPA) system, which is a potential ECL luminophore and coreactant system. AuNPs serve the role of an ECL signal enhancer as well as the carrier of antibody, which enables the creation of a label-free immunosensor for antigen−antibody interactions. The prepared immunosensor detected cTnI with a detection limit (LOD) of 0.03 ng/mL. This potential immunosensor provides appreciable results in the detection of cTnI from spiked real serum analysis, which shows its potential application in low-resource clinical settings.

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Atomic Layer Deposition of TiO₂ on Si Window Enables In Situ ATR-SEIRAS Measurements in Strong Alkaline Electrolytes

Cited by 2 publications

References 54 publications

Attenuated total reflection infrared spectroscopy for studying electrochemical cycling of hydrogen, carbon, and nitrogen-containing molecules

Attenuated total reflection infrared spectroscopy for studying electrochemical cycling of hydrogen, carbon, and nitrogen-containing molecules

Immunosensing of Cardiac Troponin I (cTnI) Using a Two-Electrode Electrochemiluminescence Platform with Near Persisting Luminescence Generated on a Ru(bpy)₃²⁺-Tripropylamine System

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Atomic Layer Deposition of TiO2 on Si Window Enables In Situ ATR-SEIRAS Measurements in Strong Alkaline Electrolytes

Cited by 2 publications

References 54 publications

Attenuated total reflection infrared spectroscopy for studying electrochemical cycling of hydrogen, carbon, and nitrogen-containing molecules

Attenuated total reflection infrared spectroscopy for studying electrochemical cycling of hydrogen, carbon, and nitrogen-containing molecules

Immunosensing of Cardiac Troponin I (cTnI) Using a Two-Electrode Electrochemiluminescence Platform with Near Persisting Luminescence Generated on a Ru(bpy)32+-Tripropylamine System

Contact Info

Product

Resources

About

Atomic Layer Deposition of TiO₂ on Si Window Enables In Situ ATR-SEIRAS Measurements in Strong Alkaline Electrolytes

Immunosensing of Cardiac Troponin I (cTnI) Using a Two-Electrode Electrochemiluminescence Platform with Near Persisting Luminescence Generated on a Ru(bpy)₃²⁺-Tripropylamine System