Atopic dermatitis: impact on quality of life and patients’ attitudes toward its management

Torrelo, Antonio; Ortiz, Javier Benítez; Alomar, A.; Ros, S.; Prieto, Marta; Cuervo, Jesús

doi:10.1684/ejd.2011.1560

Cited by 40 publications

(49 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…For most severity subcategories the reported loss of work days was considerably higher than in two other studies, which reported 5·8 days in a 6‐month period and 2·7 days per year, respectively . In the European Union, the related indirect costs due to reduced performance at work and working time missed were estimated at €2 billion per year .…”

Section: Discussionmentioning

confidence: 60%

“…For most severity subcategories the reported loss of work days was considerably higher than in two other studies, which reported 5Á8 days in a 6-month period and 2Á7 days per year, respectively. [16][17][18] In the European Union, the related indirect costs due to reduced performance at work and working time missed were estimated at €2 billion per year. 18 However, the results of the present study are consistent with a previous report, based on data from the 2013 U.S. NHWS, concluding that lost work productivity is driven mainly by presenteeism.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Increasing severity of atopic dermatitis is associated with a negative impact on work productivity among adults with atopic dermatitis in France, Germany, the U.K. and the U.S.A.

2019

View full text Add to dashboard Cite

Summary Background Atopic dermatitis (AD) is associated with high disease burden, with a significant physical and social impact. However, the association between disease severity and burden of disease, with work productivity and daily activities being one aspect, has not been well characterized. Objectives To investigate the impact of disease severity on work productivity and daily activities among adults with AD in Europe (France, Germany and the U.K.) and the U.S.A. Methods The survey panel participants for this cross‐sectional internet‐based survey on AD were sourced from the population‐based National Health and Wellness Survey (Europe 2016, U.S.A. 2015 and 2016). AD severity was determined by Patient‐Oriented Scoring Atopic Dermatitis (PO‐SCORAD). Work productivity and work activity impairment were assessed using the Work Productivity and Activity Impairment (WPAI) – Specific Health Problem questionnaire for AD. Results The study survey was completed by 1098 respondents with moderate‐to‐severe AD and 134 with mild AD. Overall, the negative impact on work productivity (all WPAI items) was suggested to increase with increasing AD severity (PO‐SCORAD) at the regional level (Europe and U.S.A.) and in the total sample. For overall work impairment due to AD, respondents with mild AD reported a mean of 2·4 h per week of potential work productivity lost, respondents with moderate AD 9·6 h and respondents with severe AD 19·0 h. Conclusions Higher AD severity was associated with a greater negative impact on work productivity in adults. This impact is a burden not only for the patient but also for society and may provide incentives for treatment optimization and more effective management of AD. What's already known about this topic? Atopic dermatitis (AD) is associated with a high disease burden. AD has a negative impact on several aspects of health‐related quality of life, one of which is work productivity. What does this study add? By using a population of participants with AD recruited from the National Health and Wellness Survey, which collects broad and representative data from the general population, survey data could be obtained from U.S. and European populations of patients with AD. The present study suggests an increasingly negative impact on work productivity with increasing severity of AD. The data indicate no regional differences in the impact of AD severity on work productivity.

show abstract

Section: Discussionmentioning

confidence: 60%

Section: Discussionmentioning

confidence: 99%

Increasing severity of atopic dermatitis is associated with a negative impact on work productivity among adults with atopic dermatitis in France, Germany, the U.K. and the U.S.A.

2019

View full text Add to dashboard Cite

show abstract

“…6 Children with AD suffer from sleep disturbance, are more irritable, require greater attention [7][8][9] and are at increased risk of mental health problems by the age of ten. 6 Children with AD suffer from sleep disturbance, are more irritable, require greater attention [7][8][9] and are at increased risk of mental health problems by the age of ten.…”

Section: Implications Of Poor Treatment Adherence In Admentioning

confidence: 99%

“…Poor treatment outcomes have significant consequences for patients and their families. 6 Children with AD suffer from sleep disturbance, are more irritable, require greater attention [7][8][9] and are at increased risk of mental health problems by the age of ten. 10 This has substantial psychosocial implications for their caregivers and families.…”

Section: Implications Of Poor Treatment Adherence In Admentioning

confidence: 99%

Factors contributing to poor treatment outcomes in childhood atopic dermatitis

Соколова

Smith

2015

Aust J Dermatology

View full text Add to dashboard Cite

Atopic dermatitis (AD) is a chronic relapsing inflammatory disease of the skin and is the most common paediatric dermatological condition. While no cure is available, it can be treated effectively if adherence to a therapeutic plan is maintained. Poor adherence to treatment is common in AD and can lead to treatment failure, which has significant impacts on the patient, family and society. A comprehensive literature search was conducted to identify factors that contribute to poor treatment adherence in childhood AD and to identify possible strategies to remedy these. Identified factors leading to poor treatment adherence include: complexity of treatment regimen, lack of knowledge, impaired quality of life, dissatisfaction with treatment strategies, infrequent follow up, corticosteroid phobia and the use of complementary and alternative medicine. Effective strategies to increase treatment adherence include: caregiver education and utilisation of education adjuncts, optimisation of the patient/caregiver-clinician relationship, early and frequent follow up and improvement of patient and caregiver quality of life.

show abstract

“…17 In fact, eczemarelated pruritus is the most common cause of chronic sleep loss in young people. 19 Scratching aside, the sensation of 'itchiness' alone impeded improvement in AD condition by causing frequent awakenings and arousals in the night time. 20 Infants with AD also exhibit signs of sleep disturbance, 9 and those who experience sleep problems are at increased risk of developing emotional and conduct problems in adolescence.…”

mentioning

confidence: 99%

Atopic dermatitis in children: management of pruritus

Blume-Peytavi¹,

Metz

2012

Acad Dermatol Venereol

View full text Add to dashboard Cite

Children with chronic atopic dermatitis (AD)-related itch require a comprehensive treatment approach that addresses the underlying cause of pruritus, as well as symptoms and complications that extend beyond the physical domain. In small children and infants, the short-term complications of quality of life disturbance and sleep dysfunction are closely associated with the course of adolescent development. In addition, the physical damage that results from uncontrolled pruritus and scratching can lead to disease chronification. Therefore, the rapid relief of acute pruritic flares, followed by the long-term maintenance of symptom-free skin, should be prioritized in AD treatment, in an effort to avoid the emotional, social and physical chronic manifestations described above. Alleviation of AD symptoms with fourth-generation topical anti-inflammatory agents like methylprednisolone aceponate is an appropriate choice of therapy for children and infants, due to its optimized therapeutic index and versatility in formulation. Especially in AD, supplemental disease management education should be considered, to address the psycho-social needs of children (and their families) suffering from pruritus.

show abstract

Atopic dermatitis: impact on quality of life and patients’ attitudes toward its management

Cited by 40 publications

References 0 publications

Increasing severity of atopic dermatitis is associated with a negative impact on work productivity among adults with atopic dermatitis in France, Germany, the U.K. and the U.S.A.

Increasing severity of atopic dermatitis is associated with a negative impact on work productivity among adults with atopic dermatitis in France, Germany, the U.K. and the U.S.A.

Factors contributing to poor treatment outcomes in childhood atopic dermatitis

Atopic dermatitis in children: management of pruritus

Contact Info

Product

Resources

About