Atopic dermatitis in the domestic dog

Pucheu‐Haston, Cherie M.

doi:10.1016/j.clindermatol.2015.10.010

Cited by 9 publications

(12 citation statements)

References 42 publications

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“…Predilection sites differ from breed to breed [ 43 ]. Even though dogs can have multiple target organs for hypersensitivities (including gut and respiratory) [ 44 ], the contact with environmental allergens predominantly induces skin lesions in this species [ 45 ]. There is no evidence for the progression of initially exclusive cutaneous lesions to respiratory signs and systemic hypersensitivities comparable to the “atopic march” in humans [ 44 ].…”

Section: Practical Approachmentioning

confidence: 99%

“…Even though dogs can have multiple target organs for hypersensitivities (including gut and respiratory) [ 44 ], the contact with environmental allergens predominantly induces skin lesions in this species [ 45 ]. There is no evidence for the progression of initially exclusive cutaneous lesions to respiratory signs and systemic hypersensitivities comparable to the “atopic march” in humans [ 44 ]. In contrast to the cat, clinical examination in the dog frequently provides clues on the pathogenesis of the pruritus as to the presence of flea bite hypersensitivity versus environmentally-induced atopy or AFR.…”

Section: Practical Approachmentioning

confidence: 99%

“…Positive reactions are frequently seen in healthy dogs on both intradermal tests [ 67 ] and serum tests for allergen-specific IgE [ 68 ]. The total serum IgE concentrations seem to have no clinical relevance in the dog [ 44 ]. Once AD is diagnosed in an animal, testing can be used in combination with clinical historical information to choose which allergens should be selected for allergen immunotherapy.…”

Section: Practical Approachmentioning

confidence: 99%

“…Due to their hair coat and compliance issues, topical treatment of dogs and cats can be difficult for owners and therefore it is less frequently used than in humans [ 44 ]. Topical glucocorticoid ointments can be used for localised skin lesions in sparsely haired areas, but prolonged application may result in skin atrophy [ 98 ].…”

Section: Practical Approachmentioning

confidence: 99%

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Atopic dermatitis in cats and dogs: a difficult disease for animals and owners

Gedon

Mueller

2018

Clin Transl Allergy

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The purpose of this review article is to give an overview of atopic dermatitis in companion animals and of recent developments including knowledge on immunological background, novel treatment options and difficulties in disease management. The prevalence of hypersensitivities seems to be increasing. The pathogenetic mechanisms are not fully understood, yet multiple gene abnormalities and altered immunological processes are involved. In dogs and cats, the diagnosis of atopic dermatitis is based on history, clinical examination and exclusion of other differential diagnoses. Intradermal testing or testing for serum allergen-specific Immunoglobulin E is only used to identify allergens for inclusion in the extract for allergen immunotherapy. Symptomatic therapy includes glucocorticoids, ciclosporin, essential fatty acids and antihistamines. A selective janus kinase 1 inhibitor and a caninized monoclonal interleukin-31 antibody are the newest options for symptomatic treatment, although longterm effects still need to be assessed. The chronic and often severe nature of the disease, the costly diagnostic workup, frequent clinical flares and lifelong treatment are challenging for owners, pets and veterinarians. Patience and excellent communication skills are needed to achieve a good owner compliance and satisfactory clinical outcome for the animal.

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Section: Practical Approachmentioning

confidence: 99%

Section: Practical Approachmentioning

confidence: 99%

Section: Practical Approachmentioning

confidence: 99%

Section: Practical Approachmentioning

confidence: 99%

See 2 more Smart Citations

Atopic dermatitis in cats and dogs: a difficult disease for animals and owners

Gedon

Mueller

2018

Clin Transl Allergy

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“…É imprescindível que haja o acompanhamento do médico veterinário, visto que, é necessário um tratamento multimodal e gestão permanente da doença crônica (PUCHEU-HASTON, 2016). Revisões periódicas das terapias adotadas e a adaptação das mesmas às necessidades do paciente devem ser realizadas, além disso, a manutenção com terapia tópica é citada como método para evitar o reaparecimento dos sinais clínicos da doença (SARIDOMICHELAKISA; OLIVRY 2016).…”

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Óbito Por Negligência No Tratamento De Dermatite Atópica: Relato De Caso

Vieira¹,

Silva²,

Porto³

et al. 2019

Enci Bio

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RESUMO Um cão, macho, SRD, adulto e portador de dermatite atópica canina, que devido à ausência da terapia de suporte e sem atendimento médico veterinário, teve seu estado bastante agravado. Ao ter sido resgatado da tutora, por uma protetora de animais, para tratamento adequado, não resistiu e veio a óbito. O animal foi encaminhado para a realização do exame anatomopatológico, durante a necroscopia observou-se múltiplas ulceras cutâneas, eritrema, presença de tricobezoar estomacal, múltiplas ulceras estomacais e intestinais associadas à gastrorragia e enterorragia. Ao exame microscópico identificou-se pneumonia intersticial crônico ativa e glomerulonefrite. A causa mortis foi por choque hipovolêmico decorrente da gastrorragia e enterorragia crônicas, ocasionadas pela presença de um piloconcremento que levou à formação das úlceras gastrointestinais. Portanto, foi possível evidenciar a negligência da tutora, permitindo que a doença evoluísse, sem encaminhar o animal ao médico veterinário para os devidos cuidados, sendo a negação do atendimento médico veterinário considerada maus tratos, de acordo como o decreto lei nº 24.645, de junho de 1934.

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