ATP-Binding Cassette Properties of Recombination Mediator Protein RecF

Korolev, Sergey

doi:10.5772/21178

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Homologous Recombination (Hr)1

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2014

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References 126 publications

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“…E. coli RecR (EcRecR) is required for EcRecO function in presynaptic complex formation in vitro, whereas EcRecF plays a regulatory role (31,32). EcRecF stimulates efficiency of EcRecA binding to the double-stranded (ds)/ ssDNA junction substrate in the presence of excess EcSSB (33,34).…”

Section: Homologous Recombination (Hr)mentioning

confidence: 99%

RecO Protein Initiates DNA Recombination and Strand Annealing through Two Alternative DNA Binding Mechanisms

Ryzhikov

Gupta

Glickman

et al. 2014

Journal of Biological Chemistry

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Background: RecO anneals DNA and initiates homologous recombination. Results: Binding of RecO to DNA/SSB is regulated by zinc during annealing and by RecR during recombination. Conclusion: Alternative DNA repair reactions are supported by different DNA binding mechanisms of RecO. Significance: Results explain how the same RMP supports multiple reactions during DNA repair and chromosome maintenance.

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