ATP Synthase: Structure, Function and Regulation of a Complex Machine

Bald, Dirk

doi:10.1007/978-94-007-0388-9_10

Cited by 4 publications

(4 citation statements)

References 126 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…7). Some bacteria use this reversed reaction to transport protons for maintaining the PMF under low oxygen conditions [27]. The F1-ATPase molecule, 8 nm in diameter and 14 nm in length, is capable of producing; 80 to 100 pN of rotary torque [11,12].…”

Section: Comparison Of Molecular Motorsmentioning

confidence: 99%

“…F1 subunit synthesize ATP when γ shaft rotates clockwise, but interestingly this enzyme subunit gives reversible rotation (anti-clockwise) of γ shaft by consuming hydrolyzing ATP separately (Fig.7). Some bacteria use this reversed reaction to transport protons for maintaining the PMF under low oxygen conditions [27]. The F1-ATPase molecule, 8 nm in diameter and 14 nm in length, is capable of producing; 80 to 100 pN of rotary torque [11,12].…”

Section: Comparison Of Molecular Motorsmentioning

confidence: 99%

“…and c subunit acts as rotor when with membrane potential. ATP synthase displays a number of mechanisms for regulation of the enzyme's activity, such as the inhibition of ATP synthase by Mg-ADP bound to the catalytic site [27].…”

Section: Comparison Of Molecular Motorsmentioning

confidence: 99%

See 2 more Smart Citations

Functions and Future Applications of F1 ATPase as Nanobioengine - Powering the Nanoworld!

Magdum¹

2013

View full text Add to dashboard Cite

show abstract

Section: Comparison Of Molecular Motorsmentioning

confidence: 99%

Section: Comparison Of Molecular Motorsmentioning

confidence: 99%

See 1 more Smart Citation

Functions and Future Applications of F1 ATPase as Nanobioengine - Powering the Nanoworld!

Magdum¹

2013

View full text Add to dashboard Cite

show abstract

“…ATP synthase is the smallest rotary motor and is embedded in membranes. In bacteria it is located on the cytoplasmic membrane whereas in eukaryotes it is embedded in the membrane of specialized organalles called mitochondria (in animal cells) and chloroplasts (in plant cells) [1848,1849,1850,1851,1852,1853,1854,1855,1856,1857,1858,1859,1861] (see appendix E for a brief introduction to these organelles and ref. [1862,1863] for the history of the discovery of ATP synthase and its mechanism from the personal perspective of some of leading contributors).…”

Section: Rotary Motor F 0 F 1 -Atpasementioning

confidence: 99%

Stochastic mechano-chemical kinetics of molecular motors: a multidisciplinary enterprise from a physicist's perspective

Chowdhury

2012

Preprint

View full text Add to dashboard Cite

A molecular motor is made of either a single macromolecule or a macromolecular complex. Just like their macroscopic counterparts, molecular motors "transduce" input energy into mechanical work. All the nanomotors considered here operate under isothermal conditions far from equilibrium. Moreover, one of the possible mechanisms of energy transduction, called Brownian ratchet, does not even have any macroscopic counterpart. But, molecular motor is not synonymous with Brownian ratchet; a large number of molecular motors execute a noisy power stroke, rather than operating as Brownian ratchet. We review not only the structural design and stochastic kinetics of individual single motors, but also their coordination, cooperation and competition as well as the assembly of multimodule motors in various intracellular kinetic processes. Although all the motors considered here execute mechanical movements, efficiency and power output are not necessarily good measures of performance of some motors. Among the intracellular nano-motors, we consider the porters, sliders and rowers, pistons and hooks, exporters, importers, packers and movers as well as those that also synthesize, manipulate and degrade "macromolecules of life". We review mostly the quantitative models for the kinetics of these motors. We also describe several of those motordriven intracellular stochastic processes for which quantitative models are yet to be developed. In part I, we discuss mainly the methodology and the generic models of various important classes of molecular motors. In part II, we review many specific examples emphasizing the unity of the basic mechanisms as well as diversity of operations arising from the differences in their detailed structure and kinetics. Multi-disciplinary research is presented here from the perspective of physicists.

show abstract

Oxygenic Photosynthesis

Shevela¹,

Björn²

2013

Natural and Artificial Photosynthesis

View full text Add to dashboard Cite

ATP Synthase: Structure, Function and Regulation of a Complex Machine

Cited by 4 publications

References 126 publications

Functions and Future Applications of F1 ATPase as Nanobioengine - Powering the Nanoworld!

Functions and Future Applications of F1 ATPase as Nanobioengine - Powering the Nanoworld!

Stochastic mechano-chemical kinetics of molecular motors: a multidisciplinary enterprise from a physicist's perspective

Oxygenic Photosynthesis

Contact Info

Product

Resources

About