2004
DOI: 10.1016/j.jchromb.2004.05.016
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ATPS applied to extraction of small molecules – polycetides – and simultaneous clarification of culture media with filamentous microorganisms

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Cited by 22 publications
(26 citation statements)
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“…Reports addressing the primary recovery of low molecular weight products using ATPS 17,29 are not common. Small molecules, particularly phytochemicals, have attracted increasing interest from the medical and scientific sector due mainly to their nutraceutical properties.…”
Section: Recovery Of Hydrophobic Low Molecular Weight Productsmentioning
confidence: 99%
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“…Reports addressing the primary recovery of low molecular weight products using ATPS 17,29 are not common. Small molecules, particularly phytochemicals, have attracted increasing interest from the medical and scientific sector due mainly to their nutraceutical properties.…”
Section: Recovery Of Hydrophobic Low Molecular Weight Productsmentioning
confidence: 99%
“…The potential of this technique for the recovery of low molecular weight non-protein products has also been addressed. 17,29 However, further characterization is required in order to realize the great potential in this field. In this context an improvement is anticipated in the characterization and development of ATPS recovery processes for this particular type of compound, mainly phytochemicals and other small molecules with nutraceutical properties.…”
Section: Potential Trends For the Application Of Atps Recovery Processesmentioning
confidence: 99%
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“…Some advantages of applying ATPS to whole culture media are the increase in recovery yields, feasibility for continuous operation, reduction of the number of steps, and decrease in the process costs because of joining clarification and partial purification 11. As far as the extraction of antibiotics is concerned, Yang et al12 reported successful extraction of cephalosporin C from whole culture medium by ATPS, separating early in the process cells and deacetyl cephalosporin C, a by‐product with a molecular structure close to the target molecule.…”
Section: Introductionmentioning
confidence: 99%
“…They have recently been used to separate biomolecules such as enzymes, other proteins and antibiotics, mainly because of the possibility of being tailored to a specific separation by varying their features and/or those of the extraction systems [10,11,18,24,25]. Their technical simplicity, easiness of scaling-up and suitability for continuous operation make this process a promising alternative for large-scale operation [17].…”
Section: Introductionmentioning
confidence: 99%