Atractylis gummifera and Centaurea ornata in the Province of Badajoz (Extremadura, Spain)—Ethnopharmacological importance and toxicological risk

Villalobos, José Ramón Vallejo; Peral, D.; Gemio, P.; Carrasco, María Consuelo; Heinrich, Michael; Pardo‐de‐Santayana, Manuel

doi:10.1016/j.jep.2009.08.036

Cited by 25 publications

(18 citation statements)

References 9 publications

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“…gummifera is an herbaceous and thorny plant (Asteraceae family) that belongs to Mediterranean countries (30,89). It is also known as blue thistle, bird-lime, chamaelon, acarna gummifera and carlina gummifera L. (89,90,91). A glue-like substance with whitish-yellowish color is secreted from this plant.…”

Section: Atractylis Gummiferamentioning

confidence: 99%

“…However, it is a well known life-threatening poisoning (89). The intoxication with A. gummifera was first described by Lefrane since 1866 (90). The major toxic constituents are two diterpenoid glycosydes: atractyloside (ATR) and carboxy-atractyloside (CATR) (90,91).…”

Section: Atractylis Gummiferamentioning

confidence: 99%

“…The intoxication with A. gummifera was first described by Lefrane since 1866 (90). The major toxic constituents are two diterpenoid glycosydes: atractyloside (ATR) and carboxy-atractyloside (CATR) (90,91). Several case reports of A. gummifera inducing toxicity were reported and most victims were children because of sweet taste of the juice of this herb (94).…”

Section: Atractylis Gummiferamentioning

confidence: 99%

See 2 more Smart Citations

Hepatotoxic Botanicals - An Evidence-based Systematic Review

Abdualmjid

Sergi

2013

J Pharm Pharm Sci

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-Purpose. Herbal medicines have been increasingly used worldwide. However, the potential harms of these herbs have been noticed most recently following hepatotoxicity with ingestion of herbal remedies. The aim of this review is to evaluate the evidence of hepatotoxic effects linked to use of herbal preparations. Method. Electronic search was performed by searching several databases: PubMed, HerbMed, Google Scholar, Scopus, Cochrane Database of Systematic Reviews and Cochrane Library using both Latin and common names of several herbs. Language was restricted to English and articles were selected for relevance reporting incidence of hepatotoxicity associated with use of herbal products in human. Results. From a total of 565 relevant reviews and articles, 254 met our inclusion criteria and were analyzed.

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Section: Atractylis Gummiferamentioning

confidence: 99%

Section: Atractylis Gummiferamentioning

confidence: 99%

Section: Atractylis Gummiferamentioning

confidence: 99%

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Hepatotoxic Botanicals - An Evidence-based Systematic Review

Abdualmjid

Sergi

2013

J Pharm Pharm Sci

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“…(Asteraceae) , Centaurea ornata Willd. (Asteraceae) , Thymus mastichina L. (Lamiaceae) [192, 193],and other more restricted such as Lilium pyrenaicum Gouan (Liliaceae) , Lithodora fruticosa (L.) Griseb. (Boraginaceae), and Phlomis lychnitis L. (Lamiaceae) [180, 190].…”

Section: Medical Ethnobotany In Europeunclassified

“…For example, this is the case for both Osmunda regalis L. (Osmundaceae) and Atractylis gummifera L. (Asteraceae) used in Cantabria and Extremadura, respectively [193, 195]. Most people hide their use of these species from their doctor in order to avoid reprimand, since many Spanish allopathic practitioners lack adequate training in CAM and phytotherapy and tend to exhibit a sense of disdain towards traditional medicine, which is commonly seen as irrelevant or even harmful [143].…”

Section: The Adaptive Nature Of Traditional Pharmacopoeiasmentioning

confidence: 99%

Medical Ethnobotany in Europe: From Field Ethnography to a More Culturally Sensitive Evidence-Based CAM?

Quave

Pardo‐de‐Santayana

Pieroni

2012

Evidence-Based Complementary and Alternative Medicine

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European folk medicine has a long and vibrant history, enriched with the various documented uses of local and imported plants and plant products that are often unique to specific cultures or environments. In this paper, we consider the medicoethnobotanical field studies conducted in Europe over the past two decades. We contend that these studies represent an important foundation for understanding local small-scale uses of CAM natural products and allow us to assess the potential for expansion of these into the global market. Moreover, we discuss how field studies of this nature can provide useful information to the allopathic medical community as they seek to reconcile existing and emerging CAM therapies with conventional biomedicine. This is of great importance not only for phytopharmacovigilance and managing risk of herb-drug interactions in mainstream patients that use CAM, but also for educating the medical community about ethnomedical systems and practices so that they can better serve growing migrant populations. Across Europe, the general status of this traditional medical knowledge is at risk due to acculturation trends and the urgency to document and conserve this knowledge is evident in the majority of the studies reviewed.

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Asteraceae Martinov

and¹,

Tyrl²

2012

Toxic Plants of North America

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Atractylis gummifera and Centaurea ornata in the Province of Badajoz (Extremadura, Spain)—Ethnopharmacological importance and toxicological risk

Cited by 25 publications

References 9 publications

Hepatotoxic Botanicals - An Evidence-based Systematic Review

Hepatotoxic Botanicals - An Evidence-based Systematic Review

Medical Ethnobotany in Europe: From Field Ethnography to a More Culturally Sensitive Evidence-Based CAM?

Asteraceae Martinov

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