2024
DOI: 10.1002/cbdv.202400817
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Atramacrolodes A−D (1–4), Four Undescribed Eudesmane‐Type Sesquiterpenes from the Rhizome of Atractylodes macrocephala

Bei Li,
Yulu Tian,
Xinyi Guo
et al.

Abstract: Four undescribed sesquiterpenes, atramacrolodes A‐D (1‐4), along with six known compounds 5‐10 were isolated from the rhizome of Atractylodes macrocephala. Compound 3 possessed a new skeleton based on an unprecedented carton‐carton connection. Their structures were determined by UV, IR, HRESIMS, NMR spectra, 13C NMR calculation with DP4+ analysis, and the comparison of experimental and calculated ECD spectra. Compounds 5 and 8 showed protective effects against paracetamol‐induced liver cell injury.

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