Atrial and Ventricular Arrhythmias in Hypertrophic Cardiomyopathy

E/eʹ ratio and left atrial area are predictors of atrial fibrillation in patients with hypertrophic cardiomyopathy

“…Atrial enlargement implies loss of normal architecture and generation of new electric circuits that predispose to the development of AF. This finding has been repeated in several studies using atrial dimension instead of atrial area . Our study is the first to consider a cutoff value for the atrial area, a parameter that is much more used in clinical practice than atrial dimension.…”

“…After performing multivariate analysis, only E/eʹ ≥ 17 ratio {HR 3.27 ([1.10–9.27] P = .033)} and atrial area {HR 1.06 ([1.01–1.13] P = .037)} remained statistically significant (Table ) (Figures 2–3). The analysis of the atrial area by the ROC curve showed that a cutoff value of 28 cm 2 has a sensitivity of 87% and a specificity of 75% to predict new‐onset AF . These results were not improved by adding left atrial area index to the analysis.…”

“…Preserved systolic function was detected in 94.2%. Median follow‐up was 3 years . Thirty‐eight patients (11.8%) developed new‐onset AF during the follow‐up period.…”

“…Atrial fibrillation (AF) is a common arrhythmia occurring in patients with hypertrophic cardiomyopathy (HCM). The prevalence of AF is variable, ranging between 7.5% and 43%, according to the population included and the follow‐up period considered . AF implies the loss of atrial contraction and atrioventricular synchrony.…”

Ventricular Tachyarrhythmias in Patients With Hypertrophic Cardiomyopathy and Defibrillators: Triggers, Treatment, and Implications

“…Sudden cardiac death (SCD) due to ventricular tachyarrhythmias is an infrequent, yet devastating consequence of hypertrophic cardiomyopathy (HCM) . HCM is the most common underlying heart disease in young athletes dying suddenly .…”