Atrial fibrillation: comorbidities, lifestyle, and patient factors

Fibrinaloid Microclots and Atrial Fibrillation

“…A very striking recent example [183] shows the role of particulate nanoplastics in atheromas and subsequent cardiac events, and it would be surprising if this were not also true for AF. While present initial and successful therapies for AF focus on anticoagulation [428], the recognition of fibrinaloid microclots as a cause and not just a consequence of AF may have significant and further therapeutic implications.…”

Bidirectional Two-Sample Mendelian Randomization Study of Association between Smoking Initiation and Atrial Fibrillation

“…Atrial fibrillation can lead to serious complications, including stroke and heart failure. It frequently occurs in patients with underlying conditions, such as coronary heart disease, hyperthyroidism, and hypertension 4 . It is also associated with unhealthy lifestyle habits, including smoking and drinking.…”

Tackling a growing healthcare challenge: atrial fibrillation epidemiology, prevention, and underlying causes

“…Three papers published in The Lancet Regional Health—Europe for the Series on “Atrial Fibrillation” provide an overview of AF with regards to preventive measures, 2 genetics, 3 and the contribution of socioeconomic and lifestyle factors. 4 …”

“…Adequate health care requires that patient-, lifestyle, and socioeconomic factors are addressed, which is discussed in the review by Shantsila et al. 4 The authors note that obesity increases AF risk and subsequent weight loss may reduce both symptoms and rate of recurrence, and that modifiable risk factors such as smoking and alcohol consumption also play an important role. A wide range of comorbidities are associated with AF: Hypertension, ischaemic heart disease, diabetes and chronic obstructive lung disease, leading to polypharmacy in many patients.…”