Atrial fibrillation in acute heart failure: A position statement from the Acute Cardiovascular Care Association and European Heart Rhythm Association of the European Society of Cardiology

Görenek, Bülent; Halvorsen, Sigrun; Kudaiberdieva, Gulmira; Bueno, Héctor; Gelder, Isabelle C. Van; Lettino, Maddalena; Marı́n, Francisco; Masip, Josep; Mueller, Christian; Okutucu, Sercan; Poess, Janine; Potpara, Tatjana; Price, Susanna; Lip, Gregory Y. H.

doi:10.1177/2048872619894255

Cited by 50 publications

(17 citation statements)

References 51 publications

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“…[2][3][4] Nonetheless, AF patients also commonly suffer from other cardiovascular events, including heart failure (HF) and myocardial infarction (MI). 5,6 Several risk prediction rules have been described for AF, mainly focused on stroke and bleeding risk prediction. 7,8 All clinical risk prediction rules only have modest predictive value for identifying the high-risk patients that sustain events, thus biomarkers have been added to some clinical risk factors to improve their predictive ability for outcomes, and such biomarkers or biomarker-based risk scores have been recommended in guidelines.…”

Section: Introductionmentioning

confidence: 99%

Predicting Adverse Events beyond Stroke and Bleeding with the ABC-Stroke and ABC-Bleeding Scores in Patients with Atrial Fibrillation: The Murcia AF Project

et al. 2020

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Background The ABC (age, biomarkers, and clinical history)-stroke and ABC-bleeding are biomarker-based scores proposed to predict stroke and bleeding, but non-specificity of biomarkers is common, predicting different clinical events at the same time. We assessed the predictive performance of the ABC-stroke and ABC-bleeding scores, for outcomes beyond ischemic stroke and major bleeding, in a cohort of atrial fibrillation (AF) patients. Methods We included AF patients stable on vitamin K antagonists for 6 months. The ABC-stroke and ABC-bleeding were calculated and the predictive values for myocardial infarction (MI), acute heart failure (HF), a composite of cardiovascular events, and all-cause deaths were compared. Results We included 1,044 patients (49.2% male; median age 76 [71–81] years). During 6.5 (4.3–7.9) years, there were 58 (5.6%) MIs, 98 (9.4%) acute HFs, 167 (16%) cardiovascular events, and 418 (40%) all-cause deaths. There were no differences in mean ABC-stroke and ABC-bleeding scores in patients with/without MI (p = 0.367 and p = 0.286, respectively); both scores were higher in patients with acute HF, cardiovascular events, or death (all p < 0.05). Predictive performances for the ABC-stroke and ABC-bleeding scores were similar, ranging from “poor” for MI (c-indexes ∼0.54), “moderate” for acute HF and cardiovascular events (c-indexes ∼0.60 and ∼0.64, respectively), and “good” for all-cause mortality (c-indexes > 0.70). Clinical usefulness whether assessed by ABC-stroke or ABC-bleeding was similar for various primary endpoints. Conclusion In AF patients, the ABC-stroke and ABC-bleeding scores demonstrated similar predictive ability for outcomes beyond stroke and bleeding, including MI, acute HF, a composite of cardiovascular events, and all-cause deaths. This is consistent with nonspecificity of biomarkers that predict “sick” patients or poor prognosis overall.

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Section: Introductionmentioning

confidence: 99%

Predicting Adverse Events beyond Stroke and Bleeding with the ABC-Stroke and ABC-Bleeding Scores in Patients with Atrial Fibrillation: The Murcia AF Project

et al. 2020

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“…Niz preporuka stručnih društava rezimiralo je ulogu slikovnih metoda 12 ili liječenja AHF-a u specifičnim situacijama, kao što su akutni koronarni sindrom 67 ili fibrilacija atrija. 68…”

Section: Specifične Situacijeunclassified

“…A number of position papers have summarized the role of imaging 12 or the management of AHF in specific situations, such as acute coronary syndromes 67 or atrial fibrillation. 68…”

Section: Acute Heart Failurementioning

confidence: 99%

The year in cardiovascular medicine 2020: heart failure and cardiomyopathies

Bueno

Moura

Lancellotti

et al. 2021

European Heart Journal

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“…Auch hier sollte neben einer evtl. notwendigen permanenten Schrittmacherversorgung eine antithrombotische Therapie erwogen werden, die risikoadaptiert und unter Berücksichtigung möglicher Blutungskomplikationen über die Akutsituation hinaus weitergeführt werden sollte [19].…”

Section: Merkeunclassified