Atrial Fibrillation in Acute St-Elevation Myocardial Infarction: Clinical and Prognostic Features

Abstract

Atrial fibrillation (AF) is a common arrhythmia in the setting of acute coronary syndrome and acute ST-elevation myocardial infarction (STEMI). This review summarizes recent evidence on the clinical and prognostic significance of pre-existent and new-onset AF in acute STEMI patients and highlights new emerging predictors of AF development in the era of contemporary treatment.

Association of admission serum laboratory parameters with new-onset atrial fibrillation after a primary percutaneous coronary intervention

“…Despite advanced treatment options, adverse cardiovascular events, such as NOAF, can occur during the course of STEMI. NOAF is not rare in the setting of STEMI and also recent studies have reported that NOAF is related to increased mortality and morbidity after primary PCI [3]. In our study, NOAF was found to be an independent predictor of overall mortality consistent with the literature.…”

“…Also, it is known that NOAF is related to worse outcome during the course of STEMI [3]. To date, several clinical and laboratory parameters such as advanced age, female sex, higher Killip class, low leftventricular ejection fraction (LVEF), anemia, NTproBNP, and high-sensitivity C-reactive protein (hs-CRP) have been established in the prediction of NOAF in STEMI patients [3,4].…”

Mechanisms of ST-segment elevation myocardial infarction in patients with atrial fibrillation, prior stenting and long-standing chronic coronary syndrome

“…Among patients with established CAD, the prevalence of concurrent AF is estimated at 6-8% [6,7]. Yet, AF is more frequently encountered in the setting of STEMI, encompassing approximately 14% of patients [8], and a review from Gorenek et al [9] reported that in about 2.5-4.4% of STEMI patients the arrhythmia existed prior to hospital admission. This is consistent with the present findings.…”

The incidence of atrial fibrillation in patients with coronary artery disease

“…AF je 1,24 puta ćešća kod muškaraca nego kod žena u ukupnoj populaciji koronarnih bolesnika ali je učestalost žena sa AF u infarktu nešto veća. Ovi rezulata su upravo u skladu sa suprotstavljenim nalazima drugih studija koje pokazuju da AF preovlađuje kod muškaraca 23 ali i nekih koji nalaze da žene češće imaju AF 1,10,33 .…”