Atrial Fibrillation in End‐Stage Renal Disease

Korantzopoulos, Panagiotis; Kokkoris, Stelios; Liu, Tong; Protopsaltis, Ioannis; Li, Guangping; Goudevenos, John

doi:10.1111/j.1540-8159.2007.00877.x

Cited by 40 publications

(41 citation statements)

References 57 publications

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“…31,32 Furthermore, whether through the predisposition to AF or as a marker of chronic LV diastolic impairment, recent evidence confirms an association between LA dilatation and increased mortality in ESRF patients with LV hypertrophy. [32][33][34] Our study would support the conclusion that changes in atrial dimension following AVF-creation may play a significant role in the promotion of atrial arrhythmia within the ESRF milieu.…”

supporting

confidence: 73%

The deleterious effects of arteriovenous fistula-creation on the cardiovascular system: a longitudinal magnetic resonance imaging study

Dundon¹,

Torpey²,

Nelson³

et al. 2014

IJNRD

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Aim: Arteriovenous fistula-formation remains critical for the provision of hemodialysis in endstage renal failure patients. Its creation results in a significant increase in cardiac output, with resultant alterations in cardiac stroke volume, systemic blood flow, and vascular resistance. The impact of fistula-formation on cardiac and vascular structure and function has not yet been evaluated via "gold standard" imaging techniques in the modern era of end-stage renal failure care. Methods: A total of 24 patients with stage 5 chronic kidney disease undergoing fistula-creation were studied in a single-arm pilot study. Cardiovascular magnetic resonance imaging was undertaken at baseline, and prior to and 6 months following fistula-creation. This gold standard imaging modality was used to evaluate, via standard brachial flow-mediated techniques, cardiac structure and function, aortic distensibility, and endothelial function. , and left ventricular mass were observed (12.7% increase) (P,0.01). Endothelial-dependent vasodilation was significantly decreased at follow up (9.0%±9% vs 3.0%±6%) (P=0.01). No significant change in aortic distensibility was identified. Conclusion:In patients with end-stage renal failure, fistula-formation is associated with an increase in cardiac output, dilation of all cardiac chambers and deterioration in endothelial function.

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supporting

confidence: 73%

The deleterious effects of arteriovenous fistula-creation on the cardiovascular system: a longitudinal magnetic resonance imaging study

Dundon¹,

Torpey²,

Nelson³

et al. 2014

IJNRD

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“…The estimated prevalence of AF in these patients is reported to be in the range of 7.0–27.0% [8,9]. Ananthapanyasut et al [10] reported a 21.2% (n = 214) incidence of AF among 1,010 nondialysis CKD patients.…”

Section: Discussionmentioning

confidence: 99%

Clinical Characteristics and Cardiovascular Outcomes of Hemodialysis Patients with Atrial Fibrillation: A Prospective Follow-Up Study

Fujii

Kim²,

Kawaguchi³

et al. 2011

Am J Nephrol

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Background/Aims: Among the cardiovascular complications in dialysis patients, atrial fibrillation (AF) is the most common arrhythmia. The purpose of this study was to clarify the characteristics and mortality of hemodialysis patients with AF, which are not completely elucidated. Methods: The prevalence of AF in patients undergoing hemodialysis in our institutions was assessed. Patients with AF (AF group) and without AF (control group) were included in this study. Patients in the control group were matched for several important clinical risk factors. For further analysis, AF patients were divided into two groups on the basis of the type of AF (chronic AF (CAF) and paroxysmal AF (PAF) groups). These patients were evaluated for their clinical characteristics, laboratory data and echocardiographic parameters and prospectively followed up for 48 months. Results: Among 328 study patients, 30 had AF (9.1%). Left atrial diameter (LAD) and the left ventricular mass index were significantly greater in the AF group than in the control group. Furthermore, cardiovascular and all-cause mortality and cumulative incidence of cardiovascular events were significantly higher in the AF group than in the control group, and tended to be higher in the CAF group. Conclusions: Our findings demonstrated that the prevalence of AF as 9.1% in hemodialysis patients, and that AF, especially CAF, were associated with high mortality.

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“…In a study of Korantzopoulos P et al the incidence of AF in patients with end stage renal disease (ESRD) is between 1 and 4.1 per 100 patient-years 22 . Vazquez et al extended previous observations to report on the prevalence and incidence of AF in a cohort of patients who started dialysis at that group's center and who were followed for a mean period of 2 years.…”

Section: Resultsmentioning

confidence: 99%

Patterns of Cardiac Arrhythmia in Haemodialysis Patients

Mahmood

Haq

Giasuddin

et al. 2017

Anwer Khan Mod Med Coll J

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Background: Cardiovascular disorders are one of the most serious problems in chronic haemodialysis patients. According to the records of last 15 years, 50% of these patients died from cardiovascular complications every year, without a marked reduction in the annual frequency of deaths. Cardiac arrhythmias are frequently associated with haemodialysis and have been reported to be seen in some series in up to 76% of patients.Materials & Methods: They appear to occur mostly after the first 3 hours of dialysis. In this study we have evaluated the arrhythmias that occured before and during dialysis to reduce the burden of morbidity and mortality of the patients. This is a cross sectional descriptive type of observational study on haemodialysis patients in Medical College for Women and Hospital (MCWH). Duration of study was 2 years, from July 2011 to June 2013.All the patients of end stage renal disease (ESRD) on maintenance haemodialysis (MHD) were included in the study. 81 patients were included to the study. One patient had permanent pacemaker and was excluded. Four patients had died during the study and four patients did not co-operated and left the study. Holter monitoring of a patient was unreadable because of artifact. Finally 71 patients were studied.Results: Out of 71 patients 38 were males and 33 were females with male to female ratio of 1.5:1. The mean age of the patient was 50.81 12.45 ( Range-22-75 ) year. Among 71 patients 19 had both DM and HTN and 42 patients had only HTN and 10 patients had other causes of chronic kidney disease (CKD).Premature atrial contraction(PAC) 27(40.30%) and Premature ventricular contraction(PVC) 40(59.70%)were the most common arrhythmia in dialysis patients before and during dialysis in our study. We found no significant effect of heamodialysis (HD) on cardiac arrhythmia. There was no correlation between arrhythmia and changes in Hb%, HbA1C, S. Albumin, S Creatinine, ions changes(Na+, K+, Ca++, Mg++)before and during haemodialysis (HD). QT intervals had no significant increase in dialysis patients. The prevalence of Atrial fibrillation (AF) rhythm was 5.63%.A high prevalence of cardiovascular disease is observed in end stage renal disease(ESRD) patients receiving dialysis therapy.Conclusion: The number of arrhythmias did not increase during dialysis in patients with no history of cardiac diseases, so the dialysis itself is not a leading risk factor for arrhythmias. But if a patient has history of arrhythmia, ischemia or left ventricular hypertrophy(LVH), he should be monitored during haemodialysis or undergo peritoneal dialysis in order to reduce the arrhythmia risk.Anwer Khan Modern Medical College Journal Vol. 7, No. 1: Jan 2016, P 28-33

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Atrial Fibrillation in End‐Stage Renal Disease

Cited by 40 publications

References 57 publications

The deleterious effects of arteriovenous fistula-creation on the cardiovascular system: a longitudinal magnetic resonance imaging study

The deleterious effects of arteriovenous fistula-creation on the cardiovascular system: a longitudinal magnetic resonance imaging study

Clinical Characteristics and Cardiovascular Outcomes of Hemodialysis Patients with Atrial Fibrillation: A Prospective Follow-Up Study

Patterns of Cardiac Arrhythmia in Haemodialysis Patients

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