Atrial Fibrillation Is Associated with Decreased Cardiac Sympathetic Response to Isometric Exercise in CHF in Comparison to Sinus Rhythm

Gould, Paul A.; Esler, Murray; Kaye, David M.

doi:10.1111/j.1540-8159.2008.01152.x

Cited by 12 publications

(6 citation statements)

References 27 publications

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“…Another study showed baroreflex sensitivity indices were significantly lower in the HUTT-positive group than in the HUTT-negative group, 8) and a blunted baroreflex associated with AF was demonstrated in patients with chronic heart failure as compared to patients with sinus rhythm. 30) In our study, in addition to a positive HUTT, we also found that increased left atrial diameter, duration of AF history, and sleep apnea were independent predictors of AF recurrence. These data were in line with previous findings.…”

Section: Discussionsupporting

confidence: 71%

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et al. 2015

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Autonomic dysfunction has been associated with paroxysmal atrial fibrillation (PAF). The head-up tilt test (HUTT) is an important diagnostic tool for autonomic dysfunction. The aim of this study was to examine atrial fibrillation recurrence after RFCA by performing HUTT. A total of 488 consecutive patients with PAF who underwent RFCA were prospectively enrolled. HUTT was positive in 154 (31.6%) patients after a mean follow-up of 22.7 ± 3.5 months, and 163 (33.4%) had a recurrence. HUTT positive was significantly higher in PAF patients with recurrence compared to those without (68 (41.7%) versus 86 (26.5%), P < 0.001). Multivariate Cox regression analysis revealed that HUTT positive (HR: 1.96; 95% CI: 1.49-2.48, P < 0.001), left atrial diameter (HR: 1.77; 95%CI: 1.15-2.11, P = 0.004), AF duration (HR: 1.27; 95%CI: 0.98-1.83, P = 0.014), and sleep apnea (HR: 1.02; 95%CI: 0.81-1.53, P = 0.032) were independent predictors of clinical recurrence after RFCA. The success rate of ablation was 70.4% in patients in the HUTT negative group compared with 58.4% in patients in the HUTT positive group (log-rank P = 0.006). Patients with a positive headup tilt test were at an increased risk of AF recurrence after catheter ablation. Our results suggest that HUTT was a significant predictor for AF recurrence after catheter ablation for PAF.

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Section: Discussionsupporting

confidence: 71%

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et al. 2015

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“…Our findings are coherent with several previous studies reporting an association between altered autonomic nervous system functions and development of AF. Stimulation of the parasympathetic ganglia have been shown to play a critical role in triggering AF episodes 36,37 and heart failure patients with AF exhibit an altered sympathetic response to exercise compared with heart failure patients in sinus rhythm 38 . These alterations in the autonomic nervous system functions seem to precede the development of AF, perhaps explaining the predictive power of these measures.…”

Section: Discussionmentioning

confidence: 99%

Autonomic Dysfunction and New‐Onset Atrial Fibrillation in Patients With Left Ventricular Systolic Dysfunction After Acute Myocardial Infarction: A CARISMA Substudy

Jøns

Raatikainen

Gang

et al. 2010

Cardiovasc electrophysiol

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“…Studies looking at the effects of exercise training on individuals with AF report an increased exercise capacity through 6MWT distance and significantly decreased resting HR [176][177][178] .…”

Section: Appendix J: Extra Considerations For Individuals With Atrialmentioning

confidence: 99%

ECG changes during ISWTs in adult patients commencing CR: a retrospective case note review

et al. 2021

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In order to challenge inequalities and mainstream equality in health, individual feedback on the CR services provided should be sought at appropriate intervals 1,4,10,11. In addition, to meet the individual's psychosocial needs and to create the best possible chances of uptake, long-term adherence and self-management of a physically active lifestyle, the BACPR Standards and Core Components recommend that a choice of CR venue (hospital, community or home) is offered 5. Key national guidelines associated with cardiac rehabilitation A number of key publications guide the design and implementation of CR as summarised below: Group Guideline/Policy Website General (all)  Scottish Intercollegiate Guidelines Network (SIGN) guidelines for CR (2002)  American Association of Cardiovascular and Pulmonary Rehabilitation (AACVPR) (2006)  American College of Sports Medicine (ACSM) (2009)  Joint British Societies' (JBS3) Consensus recommendations for the prevention of cardiovascular disease 2014

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Atrial Fibrillation Is Associated with Decreased Cardiac Sympathetic Response to Isometric Exercise in CHF in Comparison to Sinus Rhythm

Cited by 12 publications

References 27 publications

Head-Up Tilt

Head-Up Tilt

Autonomic Dysfunction and New‐Onset Atrial Fibrillation in Patients With Left Ventricular Systolic Dysfunction After Acute Myocardial Infarction: A CARISMA Substudy

ECG changes during ISWTs in adult patients commencing CR: a retrospective case note review

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