Atrial fibrillation risk factors in patients with ischemic stroke

Abstract

Introduction: Atrial fibrillation (AF) is the most common heart arrhythmia. The condition is known to increase the risk of ischemic stroke (IS). Classical risk factors for the development of AF include advanced age, hypertension, diabetes mellitus, coronary heart disease and lipid metabolism disorders. Importantly, these are also recognized risk factors for ischemic stroke. Therefore, the purpose of this study was to investigate AF risk factors in patients with IS. Material and methods: This is single-centre retrospective study which included 696 patients with acute ischemic stroke and nonvalvular atrial fibrillation and 1678 patients with acute ischemic stroke without atrial fibrillation. Results: In this study we found-based on a univariable and multivariable logistic regression model-that compared to the patients with IS without AF, the group of patients which suffered from IS with nonvalvular atrial fibrillation (NVAF) had a higher proportion of patients who smoked cigarettes (OR = 15.742, p < 0.01; OR = 41.1, p < 0.01), had hypertension (OR = 5.161, p < 0.01; OR = 5.666, p < 0.01), history of previous stroke (OR = 3.951, p < 0.01; OR = 4.792, p < 0.01), dyslipidemia (OR = 2.312, p < 0.01; OR = 1.592, p < 0.01), coronary heart disease (OR = 2.306, p < 0.01; OR = 1.988, p < 0.01), a greater proportion of female patients (OR = 1.717, p < 0.01; OR = 2.095, p < 0.01), higher incidence of diabetes mellitus (OR = 1.341, p < 0.01; OR = 1.261, p = 0.106) and more patients in old age (OR = 1.084, p < 0.01; OR = 1.101, p < 0.01). Conclusions: Our study demonstrates a need for thorough and systematic monitoring of post-ischemic stroke patients in whom AF has not been detected and who display other important risk factors. Regardless of the stroke, these factors may be responsible for development of AF.

Mobile Single-Lead Electrocardiogram Technology for Atrial Fibrillation Detection in Acute Ischemic Stroke Patients

“…AIS patients included in the study were relatively young-64.4 years old, on average. Although some risk factors are the same for the embolic and thrombotic strokes, AF is leading cause of stroke among older patients (>75 years) [61,62]. In the present study, 40 elder patients (75 years old) were excluded from the study because they were unable to use KM device for unclear reasons.…”

Clinical comparison of intravenous thrombolysis and bridging artery thrombectomy in hyperacute ischemic stroke with unknown time of onset

“…There was no statistical significance in age, sex, previous history with hypertension, diabetes, atrial fibrillation ratio [ 6 ], expression level of glycosylated hemoglobin, blood glucose, triglyceride, total cholesterol, low density lipoprotein [ 7 ], blood homocysteine, fibrinogen level, preoperative NIHSS score, the Trial of Org in Acute Stroke Treatment (TOAST) [ 8 ] etiological classification of stroke and baseline characteristics ( Appendix ).…”

Ischemic Stroke Risk Factors in Patients with Atrial Fibrillation Treated with New Oral Anticoagulants

“…Others are modifiable—hypertension, coronary artery disease, heart failure, diabetes, or atherosclerosis [ 15 , 16 , 17 , 18 , 19 ]. Importantly, these AF risk factors are also risk factors for ischemic stroke [ 20 ]. Therefore, the aim of this study was to investigate the pattern of non-modifiable and modifiable risk factors for ischemic stroke in patients with nonvalvular atrial fibrillation (NVAF) treated with NOACs.…”