Atrial regulation of intravascular volume: Observations on the tachycardia-polyuria syndrome

Left atrial systolic function is depressed in idiopathic and preserved in ischemic dilated cardiomyopathy

“…However, despite their similarities, the two conditions may differ in the response to treatment with b-blockers [37] and possibly with angiotensin converting enzyme inhibitors [36,38] as well as in the clinical outcome [39]. Moreover, left atrial systolic function is of outmost importance for the maintenance of cardiovascular homeostasis [40], left atrial size and systolic function are related to exercise capacity [41] and prognosis [42], and medical treatment is more effective in patients with severe myocardial impairment [43]. It is reasonable therefore to assume that the better response of idiopathic compared to ischemic dilated cardiomyopathy to b-blockers and angiotensin converting enzyme inhibitors may be partly a result of a significant improvement in left atrial systolic performance in the former.…”

Characteristics of the Acute Rise of Atrial Natriuretic Factor During Ventricular Pacing

“…In addition to hemodynamic changes, atrial distention also commonly causes a diuresis. 37 Although this study was not designed to asses the urinary response to ventricular pacing, it was apparent that several patients exhibited a significant diuresis during VVI pacing and the entire study group appeared to show an increase in urinary flow rates. Given the known decrease in cardiac output during VVI pacing, this preliminary observation is of considerable interest.…”

Nocturnal polyuria in community‐dwelling women

“…It is postulated that a loss of the diurnal rhythm of arginine vasopressin in the elderly contributes to nocturnal polyuria; this has been termed ‘the nocturnal polyuria syndrome’[21]. ANP is produced by cardiac atrial myocytes and secreted in response to atrial distension and tachycardia [22,23]. It reduces renin activity and aldosterone synthesis, producing a diuresis and natriuresis [24].…”