Atrioventricular Plane Displacement and Left Ventricular function

Alam, Mahbubul; Rosenhamer, G.

doi:10.1016/s0894-7317(14)80276-9

Cited by 72 publications

(43 citation statements)

References 34 publications

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“…MG patients had a significantly lower early diastolic AV-plane velocity before pyridostigmine than controls. Changes in early diastolic AV-plane velocity can identify changes in left ventricular diastolic function not detectable by measurement of left ventricular EF or transmitral early to late filling ratio (E:A-ratio) [1,15,20,21,23,34]. Even though early diastolic AV-plane velocity tended to decrease with increasing age, duration of MG symptoms was an independent determinant for the reduction of early diastolic AV-plane velocity, supporting the suggestion of an MG-related change in cardiac function [20].…”

Section: Discussionmentioning

confidence: 66%

Left ventricular long-axis function in myasthenia gravis

et al. 2008

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Myasthenia gravis (MG) primarily affects skeletal muscles, but influence on cardiac function has been suggested. The aim of this study was to assess left ventricular long-axis function in MG patients compared to healthy controls, and to examine whether any MG-related heart involvement was influenced by the acetylcholine-esterase inhibitor pyridostigmine. We found that early diastolic atrioventricular-plane velocity and tissue Doppler peak systolic strain was lower in MG patients than in controls before pyridostigmine. The differences disappeared following administration of pyridostigmine. Also, tissue velocities at systole and early diastole tended to be lower in patients before pyridostigmine. In multivariate analyses adjusting for between-group differences in blood pressure, MG was no longer associated with lower longaxis function. Conventional echocardiographic measures of left ventricular diastolic and systolic function did not differ between groups. In conclusion, this study, using modern tissue Doppler imaging as well as conventional echocardiography, could not demonstrate definite MG-related cardiac involvement in a group of MG patients without known cardiac disease, but indicates that pyridostigmine-responsive MG-related alterations in cardiac muscle function exist in MG patients.

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Section: Discussionmentioning

confidence: 66%

Left ventricular long-axis function in myasthenia gravis

et al. 2008

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“…As contractile weakening progresses, clinical deterioration becomes evident [31]. However, the specific mechanism(s) underlying the development of RV failure secondary to PH remains unclear.Several studies have demonstrated a close correlation between mitral annular descent and left ventricular ejection fraction [20,[32][33][34]. Similarly, measurements of TAPSE have also been found to correlate with Simpson's RVejection fraction [21,[35][36][37].…”

mentioning

confidence: 83%

Delayed tricuspid valve ascent and descent components in pulmonary hypertension

López‐Candales

Gulyasy

Edelman

et al. 2009

International Journal of Cardiology

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“…One potential reason for this underestimation is the use of a single fixed region of interest (ROI) drawn at end-diastole, which does not account for valve plane motion (base toward apex) during systole [22•,26]. This shortening motion of the heart is more pronounced in vigorously contracting ventricles [28][29][30][31]. If this motion is not considered during the analysis of LVEF analysis, inclusion of counts from above the aortic valve plane within the LV ROI during systole, result in a lower calculated LVEF.…”

Section: Comparison Of Radionuclide Techniquesmentioning

confidence: 99%

Measurement of ventricular function with radionuclide techniques

Williams

2003

Curr Cardiol Rep

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The noninvasive assessment of resting left ventricular performance has become an integral part of the evaluation of patients with known or suspected cardiac disease, having important diagnostic, therapeutic, and prognostic significance. This article details the wide range of clinical diagnostic possibilities available by dynamic imaging of myocardial function using scintigraphic techniques, including gated planar and tomographic blood pool imaging, first-pass radionuclide angiography, and gated tomographic perfusion imaging. The clinical and technical aspects described should be useful to the cardiologist intent upon supervising the performance of these tests, as well as providing their interpretation.

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Atrioventricular Plane Displacement and Left Ventricular function

Cited by 72 publications

References 34 publications

Left ventricular long-axis function in myasthenia gravis

Left ventricular long-axis function in myasthenia gravis

Delayed tricuspid valve ascent and descent components in pulmonary hypertension

Measurement of ventricular function with radionuclide techniques

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