Attention deficit and hyperactivity disorder and nocturnal enuresis co-occurrence in the pediatric population: a systematic review and meta-analysis

Oliveira, Adélcio C.; Athanasio, Bruno da Silva; Mrad, Flávia Cristina de Carvalho; Vasconcelos, Mônica Maria de Almeida; Albuquerque, Maicon Rodrigues; Miranda, Débora Marques de; Silva, Ana Cristina Simões e

doi:10.1007/s00467-021-05083-y

Cited by 16 publications

(11 citation statements)

References 51 publications

(111 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Children with ADHD had two times higher risks of having nocturnal enuresis than healthy controls. [106]. Reviews suggested that the findings were inconsistent for the relation between early signs of deviating motor functioning or development and later ADHD [107, 108] and on anxiety and social functioning in children and adolescents with ADHD [109].…”

Section: Resultsmentioning

confidence: 99%

A systematic meta-review of systematic reviews on attention deficit hyperactivity disorder

Chaulagain,

Lyhmann,

Halmøy

et al. 2023

Eur. Psychiatr.

View full text Add to dashboard Cite

Background There are now hundreds of systematic reviews on attention deficit hyperactivity disorder (ADHD) of variable quality. To help navigate this literature, we have reviewed systematic reviews on any topic on ADHD. Methods We searched MEDLINE, PubMed, PsycINFO, Cochrane Library, and Web of Science and performed quality assessment according to the Joanna Briggs Institute Manual for Evidence Synthesis. A total of 231 systematic reviews and meta-analyses met the eligibility criteria. Results The prevalence of ADHD was 7.2% for children and adolescents and 2.5% for adults, though with major uncertainty due to methodological variation in the existing literature. There is evidence for both biological and social risk factors for ADHD, but this evidence is mostly correlational rather than causal due to confounding and reverse causality. There is strong evidence for the efficacy of pharmacological treatment on symptom reduction in the short-term, particularly for stimulants. However, there is limited evidence for the efficacy of pharmacotherapy in mitigating adverse life trajectories such as educational attainment, employment, substance abuse, injuries, suicides, crime, and comorbid mental and somatic conditions. Pharmacotherapy is linked with side effects like disturbed sleep, reduced appetite, and increased blood pressure, but less is known about potential adverse effects after long-term use. Evidence of the efficacy of nonpharmacological treatments is mixed. Conclusions Despite hundreds of systematic reviews on ADHD, key questions are still unanswered. Evidence gaps remain as to a more accurate prevalence of ADHD, whether documented risk factors are causal, the efficacy of nonpharmacological treatments on any outcomes, and pharmacotherapy in mitigating the adverse outcomes associated with ADHD.

show abstract

Section: Resultsmentioning

confidence: 99%

A systematic meta-review of systematic reviews on attention deficit hyperactivity disorder

Chaulagain,

Lyhmann,

Halmøy

et al. 2023

Eur. Psychiatr.

View full text Add to dashboard Cite

show abstract

“…The genetic, physiological, and neurological mechanism of this association has not been clarified yet. 4 Although there are studies in the literature showing that methylphenidate is effective in the treatment of enuresis accompanying ADHD, cases of enuresis occurring during the use of methylphenidate have been reported, albeit rarely. [7][8][9][10][11] In our case, immediate-release methylphenidate (10 mg and 20 mg) and ER-MPH (27 mg and 36 mg) were used after diagnosis in the past years, but enuresis did not develop.…”

Section: Discussionmentioning

confidence: 99%

“…Enuresis is a very common condition in children with ADHD. The genetic, physiological, and neurological mechanism of this association has not been clarified yet 4 . Although there are studies in the literature showing that methylphenidate is effective in the treatment of enuresis accompanying ADHD, cases of enuresis occurring during the use of methylphenidate have been reported, albeit rarely 7–11 …”

Section: Discussionmentioning

confidence: 99%

Case Report: Dose-Dependent Enuresis in Methylphenidate Use

2022

View full text Add to dashboard Cite

ObjectivesAttention deficit hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders of childhood. Although enuresis is a very common disorder in child diagnosed with ADHD, it may also develop because of methylphenidate.MethodsAuthors report here on a child case of ADHD that developed a probable enuresis related to methylphenidate.Results and ConclusionsClinicians should be aware that methylphenidate used in ADHD causes dose-dependent enuresis.

show abstract

“…10 Nocturnal enuresis is frequently observed in children with ADHD. 11 Obtained as results of their study that el 13.72% of children with ADHD had associated enuresis. 12 Enuresis is a worrying problem for children due to the risk of lower quality of life and low self-esteem, and because of the low tolerance of their relatives.…”

Section: Discussionmentioning

confidence: 99%

Nocturnal enuresis in an adolescent with anxiety disorder during the pandemic of the COVID-19, about a clinical case

Cordova¹,

Sánchez-Alegría²,

Zegarra³

2022

IPMRJ

View full text Add to dashboard Cite

We present the case of an adolescent with nocturnal enuresis since childhood, and anxiety symptoms during adolescence associated with psychosocial factors and family dynamics. During the COVID-19 pandemic, he presented intense symptoms of anxiety in relation to the fear of having a serious illness and the fear of dying, which is why he was taken to the emergency room on several occasions. Exacerbating the symptoms of enuresis and presenting the anxiety disorder due to illness. Responding favorably to antidepressant drugs, individual and family psychotherapy. Being nocturnal enuresis a rare elimination disorder in adolescence, whose diagnosis and treatment are important due to the risk of affecting psychosocial functioning and greater probability of presenting comorbidity. Likewise, we mention the impact of the COVID-19 pandemic on adolescents, due to a higher risk of presenting anxiety, depression and stress associated with enuresis.

show abstract

Attention deficit and hyperactivity disorder and nocturnal enuresis co-occurrence in the pediatric population: a systematic review and meta-analysis

Cited by 16 publications

References 51 publications

A systematic meta-review of systematic reviews on attention deficit hyperactivity disorder

A systematic meta-review of systematic reviews on attention deficit hyperactivity disorder

Case Report: Dose-Dependent Enuresis in Methylphenidate Use

Nocturnal enuresis in an adolescent with anxiety disorder during the pandemic of the COVID-19, about a clinical case

Contact Info

Product

Resources

About